The high incidence of atherosclerosis (stroke and ischemic heart disease) in patients with end-stage renal failure (ESRF), associated with clinical and/or laboratory signs of systemic inflammation, has been considered to be in part due to the long-term haemodialysis (HD). The contact with the artificial surface of the extra-corporeal circuit may promote free radicals formation, which is responsible for the increased lipid peroxidation observed in these patients. It has been also demonstrated that they have a decreased intracellular antioxidant capability. To test the presence of oxidative stress and evaluate also the antioxidant status during the dialytic session, we performed a clinical study in a group of functionally anephric patients on maintenance HD treatment with three weekly HD sessions, using a low-flux cellulose diacetate membrane and a freshly prepared bicarbonate buffer.

Plasma antioxidants modifications during haemodialysis / Bellei, E; Manfredini, P; Lucchi, L; Bergamini, S; Rota, C; Tomasi, A; Vandelli, L; Albertazzi, A; Banni, S; Iannone, A.. - (2003). ((Intervento presentato al convegno 12th European Meeting on Fat-Soluble Vitamins tenutosi a Rieti nel 13-15 Marzo 2003.

Plasma antioxidants modifications during haemodialysis

Bellei E
;
Bergamini S;Tomasi A;Albertazzi A;Iannone A.
2003

Abstract

The high incidence of atherosclerosis (stroke and ischemic heart disease) in patients with end-stage renal failure (ESRF), associated with clinical and/or laboratory signs of systemic inflammation, has been considered to be in part due to the long-term haemodialysis (HD). The contact with the artificial surface of the extra-corporeal circuit may promote free radicals formation, which is responsible for the increased lipid peroxidation observed in these patients. It has been also demonstrated that they have a decreased intracellular antioxidant capability. To test the presence of oxidative stress and evaluate also the antioxidant status during the dialytic session, we performed a clinical study in a group of functionally anephric patients on maintenance HD treatment with three weekly HD sessions, using a low-flux cellulose diacetate membrane and a freshly prepared bicarbonate buffer.
12th European Meeting on Fat-Soluble Vitamins
Rieti
13-15 Marzo 2003
Bellei, E; Manfredini, P; Lucchi, L; Bergamini, S; Rota, C; Tomasi, A; Vandelli, L; Albertazzi, A; Banni, S; Iannone, A.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1177396
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