In 2015, the International League Against Epilepsy (ILAE) proposed a new definition of status epilepticus (SE): 5 minutes of ongoing seizure activity to diagnose convulsive SE (CSE, ie, bilateral tonic-clonic SE) and 10 minutes for focal SE and absence SE, rather than the earlier criterion of 30 minutes. Based on semiology, several types of SE with prominent motor phenomena at any time (including CSE) were distinguished from those without (ie, nonconvulsive SE, NCSE). We present the first population-based incidence study applying the new 2015 ILAE definition and classification of SE and report the impact of the evolution of semiology and level of consciousness (LOC) on outcome.
Epidemiology of status epilepticus in adults: A population-based study on incidence, causes, and outcomes / Leitinger, Markus; Trinka, Eugen; Giovannini, Giada; Zimmermann, Georg; Florea, Cristina; Rohracher, Alexandra; Kalss, Gudrun; Neuray, Caroline; Kreidenhuber, Rudolf; Höfler, Julia; Kuchukhidze, Giorgi; Granbichler, Claudia; Dobesberger, Judith; Novak, Helmut F; Pilz, Georg; Meletti, Stefano; Siebert, Uwe. - In: EPILEPSIA. - ISSN 0013-9580. - 60:1(2019), pp. 53-62. [10.1111/epi.14607]
Epidemiology of status epilepticus in adults: A population-based study on incidence, causes, and outcomes
Giovannini, Giada;Meletti, Stefano;
2019
Abstract
In 2015, the International League Against Epilepsy (ILAE) proposed a new definition of status epilepticus (SE): 5 minutes of ongoing seizure activity to diagnose convulsive SE (CSE, ie, bilateral tonic-clonic SE) and 10 minutes for focal SE and absence SE, rather than the earlier criterion of 30 minutes. Based on semiology, several types of SE with prominent motor phenomena at any time (including CSE) were distinguished from those without (ie, nonconvulsive SE, NCSE). We present the first population-based incidence study applying the new 2015 ILAE definition and classification of SE and report the impact of the evolution of semiology and level of consciousness (LOC) on outcome.
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