We analyze the prognostic potential of (1 → 3)-β-D-glucan (BG) levels in predicting clinical outcomes in patients with invasive fungal infections, on a population undergoing 253 episodes (177 with positive and 76 with negative outcome). Using linear regression analysis, we assessed the prognostic potential of kinetically evaluated BG levels and we found an overall sensitivity and specificity of 68 and 82%, respectively. Moreover, using an interpretative algorithm based on two distinct cutoff values, we were able to predict the outcome in 84% of the studied population with a diagnostic accuracy of 82%.

Prognostic Potential of the Panfungal Marker (1 → 3)-β-D-Glucan in Invasive Mycoses Patients / Pini, P; Venturelli, C; Girardis, M; Forghieri, F; Blasi, E. - In: MYCOPATHOLOGIA. - ISSN 0301-486X. - 184:1(2019), pp. 147-150-150. [10.1007/s11046-018-0282-5]

Prognostic Potential of the Panfungal Marker (1 → 3)-β-D-Glucan in Invasive Mycoses Patients

Girardis, M;Blasi, E
2019

Abstract

We analyze the prognostic potential of (1 → 3)-β-D-glucan (BG) levels in predicting clinical outcomes in patients with invasive fungal infections, on a population undergoing 253 episodes (177 with positive and 76 with negative outcome). Using linear regression analysis, we assessed the prognostic potential of kinetically evaluated BG levels and we found an overall sensitivity and specificity of 68 and 82%, respectively. Moreover, using an interpretative algorithm based on two distinct cutoff values, we were able to predict the outcome in 84% of the studied population with a diagnostic accuracy of 82%.
2-lug-2018
184
1
147-150
150
Prognostic Potential of the Panfungal Marker (1 → 3)-β-D-Glucan in Invasive Mycoses Patients / Pini, P; Venturelli, C; Girardis, M; Forghieri, F; Blasi, E. - In: MYCOPATHOLOGIA. - ISSN 0301-486X. - 184:1(2019), pp. 147-150-150. [10.1007/s11046-018-0282-5]
Pini, P; Venturelli, C; Girardis, M; Forghieri, F; Blasi, E
File in questo prodotto:
File Dimensione Formato  
Pini_prognosticBG_Mycopathologia2019.pdf

non disponibili

Descrizione: Pini et al 2019_BG prognostic
Tipologia: Versione dell'editore (versione pubblicata)
Dimensione 658.89 kB
Formato Adobe PDF
658.89 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1173426
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 2
  • ???jsp.display-item.citation.isi??? 2
social impact