Review of potential improvements using MRI in the radiotherapy workflow

Torresin, A; Brambilla, MG; Monti, AF; Moscato, A; Brockmann, MA; Schad, L; Attenberger, UI; Lohr, F

doi:10.1016/j.zemedi.2014.11.003

The goal of modern radiotherapy is to deliver a lethal amount of dose to tissue volumes that contain a significant amount of tumour cells while sparing surrounding unaffected or healthy tissue. Online image guided radiotherapy with stereotactic ultrasound, fiducial-based planar X-ray imaging or helical/conebeam CT has dramatically improved the precision of radiotherapy, with moving targets still posing some methodical problems regarding positioning. Therefore, requirements for precise target delineation and identification of functional body structures to be spared by high doses become more evident. The identification of areas of relatively radioresistant cells or areas of high tumor cell density is currently under development. This review outlines the state of the art of MRI integration into treatment planning and its importance in follow up and the quantification of biological effects. Finally the current state of the art of online imaging for patient positioning will be outlined and indications will be given what the potential of integrated radiotherapy/online MRI systems is.

Data di pubblicazione:	2015
Titolo:	Review of potential improvements using MRI in the radiotherapy workflow
Autore/i:	Torresin, A; Brambilla, Mg; Monti, Af; Moscato, A; Brockmann, Ma; Schad, L; Attenberger, Ui; Lohr, F
Autore/i UNIMORE:	Torresin A Brambilla MG Monti AF Moscato A Brockmann MA Schad L Attenberger UI LOHR, Frank Reinhard Heinrich mostra contributor esterni nascondi contributor esterni
Digital Object Identifier (DOI):	10.1016/j.zemedi.2014.11.003
Rivista:	ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK
Volume:	25
Fascicolo:	3
Pagina iniziale:	210
Pagina finale:	220
Codice identificativo ISI:	WOS:000362994500003
Codice identificativo Scopus:	2-s2.0-84941023373
Codice identificativo Pubmed:	25779877
Citazione:	Review of potential improvements using MRI in the radiotherapy workflow / Torresin, A; Brambilla, Mg; Monti, Af; Moscato, A; Brockmann, Ma; Schad, L; Attenberger, Ui; Lohr, F. - In: ZEITSCHRIFT FUR MEDIZINISCHE PHYSIK. - ISSN 0939-3889. - 25:3(2015), pp. 210-220.
Tipologia	Articolo su rivista

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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11380/1172488

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