Objective: To investigate the construct validity of the Short Form-36 (SF-36) Health Survey questionnaire in obese patients. Research Methods and Procedures: Our series consisted of 1735 obese patients (age, 44.7 11.0 years; 1346 women) consecutively enrolled in the QUOVADIS study, an observational multicenter study of obese treatment-seeking outpatients. The construct validity of the SF-36 was assessed by main component analysis. Age-, gender-, and educationadjusted general linear models were used to investigate the relationship between BMI and SF-36 domains or factors identified by main component analysis. Results: BMI was significantly associated with poor healthrelated quality of life in all eight SF-36 domains, and the strongest association was observed with physical activity. Main components analysis generated a six-factor solution explaining 59% of the observed variance. BMI was strongly associated with factors based on the loading of items regarding the physical activity domain and factors based on role-physical and role-emotional items or general health and bodily pain items. In contrast, mental health-, vitality-, and social functioning-based factors were not related to BMI. Discussion: In obese treatment-seeking outpatients, the clustering of SF-36 items in main components is not significantly different from the domain-based approach generally used, thus confirming the robustness of such a generic questionnaire in this specific condition. However, the peculiar clustering of some SF-36 items and their relationship with BMI suggest that the health-related quality of life profile of subjects belonging to that population may be better described with alternative aggregations of the SF-36 items or with disease-tailored questionnaires.
|Data di pubblicazione:||2006|
|Titolo:||Construct Validity of the Short Form-36 Health Survey and Its Relationship with BMI in Obese Outpatients|
|Autore/i:||Corica, Francesco; Corsonello, Andrea; Apolone, Giovanni; Lucchetti, Maria; Melchionda, Nazario; Marchesini, Giulio; Ventura, Paolo; QUOVADIS Study Group, The|
|Digital Object Identifier (DOI):||10.1038/oby.2006.162|
|Codice identificativo ISI:||WOS:000240752200017|
|Codice identificativo Scopus:||2-s2.0-33750582422|
|Codice identificativo Pubmed:||16988086|
|Citazione:||Construct Validity of the Short Form-36 Health Survey and Its Relationship with BMI in Obese Outpatients / Corica, Francesco; Corsonello, Andrea; Apolone, Giovanni; Lucchetti, Maria; Melchionda, Nazario; Marchesini, Giulio; Ventura, Paolo; QUOVADIS Study Group, The. - In: OBESITY. - ISSN 1930-739X. - 14:8(2006), pp. 1429-1437.|
|Tipologia||Articolo su rivista|
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