Introduction: Group B streptococcus (GBS) is still a leading cause of neonatal sepsis and meningitis. It can result in death or long-term disabilities, including mental retardation and hearing or vision loss. Even if the adoption of preventive strategies significantly decreased the rate of early-onset infections, cases of GBS infection continue to occur. Methods: We determined incidence and clinical features of disease in Emilia-Romagna, a Northern region of Italy where GBS preventive strategies have been implemented. Results: The total number of live births was 12,933. Early-onset infections (EOD) were 30 (2 infants died), whereas late-onset diseases (LOD) were 26 (4 infants died), with the latter accounting for most meningitis and deaths. Risk factors were found in 12 and 7 infants with EOD and LOD respectively. 2 women. Twenty-one term mothers had antenatal screening: four were GBS colonized but 17 were culture negative. Conclusion: The incidence of EOD found in Emilia-Romagna is one of the lowest in Europe. Several early infections were still observed because of negative screening results. LODs accounted for most meningitis cases and deaths.
Le infezioni da streptococco B in Emilia-Romagna: un problema sempre più pediatrico / Berardi, A; Lugli, L; Pagano, Rossella; Biasini, A; Calanca, Fabrizio; Dodi, I; Galuppi, E; Morini, Ms; Moro, Ml; Sarti, M; Silvestrini, Deborah; Solari, E; Somenzi, P; Tridapalli, E; Rivi, C; Riva, M; Vagnarelli, F; Ferrari, F.. - In: MEDICO E BAMBINO. - ISSN 1591-3090. - (2007), pp. 123-124.