The aim of this study was to evaluate effort performance and subjective symptoms in a within-patient comparison of DDDR, DDD and VVIR pacing. A DDDR pacemaker (Synergyst II, Medtronic) was implanted in 14 patients (mean age 66.5 ± 5.0 yrs.) with sick sinus syndrome or II-III degree AV block. Seven subjects had chronotropic incompetence (maximum heart rate on exercise < 100 beats/min or maximum heart rate after i.v. atropine < 100 beats/min). All the patients underwent a symptom limited exercise test and a questionnaire score after 1 month of DDDR, DDD and VVIR pacing, in random order. The mean effort duration in DDDR was 12.6 ± 3.1 min, in VVIR 11.4 ± 3.4 min (p < 0.01 vs DDDR) and in DDD = 11.0 ± 2.9 min (p < 0.01 vs DDDR). Considering the subgroup of patients with chronotropic incompetence the same differences persisted whilst in the 6 subjects without chronotropic incompetence who completed the study DDDR pacing was statistically superior only to DDD and not to VVIR pacing. VVIR pacing was poorly tolerated since in all the groups of patients its symptom score was significantly higher compared with either DDDR or DDD pacing. In conclusion DDDR pacing is characterised by a superior maximal effort capacity in comparison with DDD pacing and VVIR pacing. In patients with chronotropic incompetence these differences are more marked. Moreover VVIR pacing appears poorly tolerated in subjective terms and in occurrence of side effects.

DDDR versus DDD and VVIR pacing: A single blind randomised evaluation of symptoms and effort performance / Capucci, A.; Cazzin, R.; Zardo, F.; Boriani, G.; Zanuttini, D.; Piccolo, E.. - In: EUROPEAN JOURNAL OF CARDIAC PACING AND ELECTROPHYSIOLOGY. - ISSN 0939-6780. - 3:3(1993), pp. 205-211.

DDDR versus DDD and VVIR pacing: A single blind randomised evaluation of symptoms and effort performance

Boriani, G.;
1993

Abstract

The aim of this study was to evaluate effort performance and subjective symptoms in a within-patient comparison of DDDR, DDD and VVIR pacing. A DDDR pacemaker (Synergyst II, Medtronic) was implanted in 14 patients (mean age 66.5 ± 5.0 yrs.) with sick sinus syndrome or II-III degree AV block. Seven subjects had chronotropic incompetence (maximum heart rate on exercise < 100 beats/min or maximum heart rate after i.v. atropine < 100 beats/min). All the patients underwent a symptom limited exercise test and a questionnaire score after 1 month of DDDR, DDD and VVIR pacing, in random order. The mean effort duration in DDDR was 12.6 ± 3.1 min, in VVIR 11.4 ± 3.4 min (p < 0.01 vs DDDR) and in DDD = 11.0 ± 2.9 min (p < 0.01 vs DDDR). Considering the subgroup of patients with chronotropic incompetence the same differences persisted whilst in the 6 subjects without chronotropic incompetence who completed the study DDDR pacing was statistically superior only to DDD and not to VVIR pacing. VVIR pacing was poorly tolerated since in all the groups of patients its symptom score was significantly higher compared with either DDDR or DDD pacing. In conclusion DDDR pacing is characterised by a superior maximal effort capacity in comparison with DDD pacing and VVIR pacing. In patients with chronotropic incompetence these differences are more marked. Moreover VVIR pacing appears poorly tolerated in subjective terms and in occurrence of side effects.
3
3
205
211
DDDR versus DDD and VVIR pacing: A single blind randomised evaluation of symptoms and effort performance / Capucci, A.; Cazzin, R.; Zardo, F.; Boriani, G.; Zanuttini, D.; Piccolo, E.. - In: EUROPEAN JOURNAL OF CARDIAC PACING AND ELECTROPHYSIOLOGY. - ISSN 0939-6780. - 3:3(1993), pp. 205-211.
Capucci, A.; Cazzin, R.; Zardo, F.; Boriani, G.; Zanuttini, D.; Piccolo, E.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1168345
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