Thirty-seven patients with ventricular tachyarrhythmias refractory to antiarrhythmic drug treatment, guided by electrophysiological testing, were submitted to implantation of a cardioverter-defibrillator by the transvenous technique. Mean age was 55 +/- 14 years and the underlying heart disease was coronary heart disease in 24 patients, cardiomyopathy or other etiologies in 11 patients. In 2 patients ventricular arrhythmias were idiopathic. Left ventricular ejection fraction was < or equal to 40% in 65% of the patients. The following devices were implanted: CPI Ventak P in 2 patients, Ventak P2 in 9 patients, Ventak PRx in 9 patients, Ventak PRxII in 2 patients, Telectronics Guardian ATP III 4215 in 9 patients, Siemens Siecure in 5 patients, Medtronic Jewel PCD in 1 patient. At implantation defibrillation threshold was lower with biphasic shocks than with monophasic shocks (17.0 +/- 3.2 vs 20.9 +/- 3.8 J, p < 0.003) and the need for subcutaneous patches was lower when biphasic shocks were employed. Operative and perioperative mortality were 0% and no significant complications were observed. During the follow-up (16 +/- 11 months) 35% of the patients had appropriate shocks and 93% of the patients with antitachycardia pacing availability (n = 15) had effective antitachycardia pacing interventions. The following complications were observed: lead failure in 4 patients (3 insulation breaks and 1 elongation for stretching), late lead dislodgement in 2 patients, lead recall in 1 patient, all of which required reintervention. Inappropriate shocks occurred in 30% of the patients and were related to lead failure, supraventricular arrhythmias or alternating current interference. During the follow-up one patient died of sudden death and one was submitted to heart transplantation. In conclusion, implantation of a cardioverter-defibrillator by the transvenous technique is a procedure relatively free from complications. During the follow-up lead failure appears to be one of the most relevant complications. Antitachycardia pacing allows effective termination of ventricular tachycardias without cardioversion, with a better compliance.

Cardioverter-defibrillatori impiantati per via transvenosa: esperienza clinica all'impianto e durante il follow-up [Transvenous cardioverter-defibrillators: clinical experience at implantation and follow-up] / Boriani, G.; Frabetti, L.; Capucci, A.; Parlapiano, M.; Biffi, M.; Sabbatani, P.; Spedicato, L.; Bronzetti, G.; Pierangeli, A.; Galli, R. - In: CARDIOLOGIA. - ISSN 0393-1978. - 40:6(1995), pp. 381-389.

Cardioverter-defibrillatori impiantati per via transvenosa: esperienza clinica all'impianto e durante il follow-up [Transvenous cardioverter-defibrillators: clinical experience at implantation and follow-up]

Boriani, G.;Galli, R
1995

Abstract

Thirty-seven patients with ventricular tachyarrhythmias refractory to antiarrhythmic drug treatment, guided by electrophysiological testing, were submitted to implantation of a cardioverter-defibrillator by the transvenous technique. Mean age was 55 +/- 14 years and the underlying heart disease was coronary heart disease in 24 patients, cardiomyopathy or other etiologies in 11 patients. In 2 patients ventricular arrhythmias were idiopathic. Left ventricular ejection fraction was < or equal to 40% in 65% of the patients. The following devices were implanted: CPI Ventak P in 2 patients, Ventak P2 in 9 patients, Ventak PRx in 9 patients, Ventak PRxII in 2 patients, Telectronics Guardian ATP III 4215 in 9 patients, Siemens Siecure in 5 patients, Medtronic Jewel PCD in 1 patient. At implantation defibrillation threshold was lower with biphasic shocks than with monophasic shocks (17.0 +/- 3.2 vs 20.9 +/- 3.8 J, p < 0.003) and the need for subcutaneous patches was lower when biphasic shocks were employed. Operative and perioperative mortality were 0% and no significant complications were observed. During the follow-up (16 +/- 11 months) 35% of the patients had appropriate shocks and 93% of the patients with antitachycardia pacing availability (n = 15) had effective antitachycardia pacing interventions. The following complications were observed: lead failure in 4 patients (3 insulation breaks and 1 elongation for stretching), late lead dislodgement in 2 patients, lead recall in 1 patient, all of which required reintervention. Inappropriate shocks occurred in 30% of the patients and were related to lead failure, supraventricular arrhythmias or alternating current interference. During the follow-up one patient died of sudden death and one was submitted to heart transplantation. In conclusion, implantation of a cardioverter-defibrillator by the transvenous technique is a procedure relatively free from complications. During the follow-up lead failure appears to be one of the most relevant complications. Antitachycardia pacing allows effective termination of ventricular tachycardias without cardioversion, with a better compliance.
40
6
381
389
Cardioverter-defibrillatori impiantati per via transvenosa: esperienza clinica all'impianto e durante il follow-up [Transvenous cardioverter-defibrillators: clinical experience at implantation and follow-up] / Boriani, G.; Frabetti, L.; Capucci, A.; Parlapiano, M.; Biffi, M.; Sabbatani, P.; Spedicato, L.; Bronzetti, G.; Pierangeli, A.; Galli, R. - In: CARDIOLOGIA. - ISSN 0393-1978. - 40:6(1995), pp. 381-389.
Boriani, G.; Frabetti, L.; Capucci, A.; Parlapiano, M.; Biffi, M.; Sabbatani, P.; Spedicato, L.; Bronzetti, G.; Pierangeli, A.; Galli, R
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1168343
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