Auto-fluorescence (AF) of healthy bone tissue has recently been described. Loss of AF (LAF) has, on the contrary, been reported in necrotic bone. Further, the use of LAF as a possible guidance to distinguish viable from necrotic bone during surgical treatment of osteonecrosis has been proposed. The aim of this study is to detail 8 patients of medication-related osteonecrosis of the jaws treated through an AF-guided surgical resection. The authors also provide the histopathologic description of hypo-fluorescent and hyper-fluorescent bone in each patient. After removal of necrotic bone block, Er:YAG laser was used for vaporizing further necrotic bone, up to the detection of strongly hyper-fluorescent bone. Samples of hyper-fluorescent bone were collected around areas of necrosis. Histopathologic evaluation revealed viable bone tissue in all hyper-fluorescent specimens. On the basis of these data, AF-guided surgical resection could be effective in highlighting surgical margins of necrotic bone tissue and it might have some utility in a range of applications of bone surgery.
Auto-Fluorescence and Histopathologic Evaluation of Medication-Related Osteonecrosis of the Jaws: Perspectives for Treatment / Giovannacci, Ilaria; Vescovi, Paolo; Magnoni, Cristina; Corradi, Domenico; Corcione, Luigi; Lucchina, Alberta Greco; Mortellaro, Carmen; Nammour, Samir; Meleti, Marco. - In: THE JOURNAL OF CRANIOFACIAL SURGERY. - ISSN 1049-2275. - 30:4(2019), pp. 1039-1043.
Data di pubblicazione: | 2019 | |
Titolo: | Auto-Fluorescence and Histopathologic Evaluation of Medication-Related Osteonecrosis of the Jaws: Perspectives for Treatment | |
Autore/i: | Giovannacci, Ilaria; Vescovi, Paolo; Magnoni, Cristina; Corradi, Domenico; Corcione, Luigi; Lucchina, Alberta Greco; Mortellaro, Carmen; Nammour, Samir; Meleti, Marco | |
Autore/i UNIMORE: | ||
Digital Object Identifier (DOI): | http://dx.doi.org/10.1097/SCS.0000000000004705 | |
Rivista: | ||
Volume: | 30 | |
Fascicolo: | 4 | |
Pagina iniziale: | 1039 | |
Pagina finale: | 1043 | |
Codice identificativo ISI: | WOS:000480739000056 | |
Codice identificativo Scopus: | 2-s2.0-85067368062 | |
Codice identificativo Pubmed: | 29944562 | |
Citazione: | Auto-Fluorescence and Histopathologic Evaluation of Medication-Related Osteonecrosis of the Jaws: Perspectives for Treatment / Giovannacci, Ilaria; Vescovi, Paolo; Magnoni, Cristina; Corradi, Domenico; Corcione, Luigi; Lucchina, Alberta Greco; Mortellaro, Carmen; Nammour, Samir; Meleti, Marco. - In: THE JOURNAL OF CRANIOFACIAL SURGERY. - ISSN 1049-2275. - 30:4(2019), pp. 1039-1043. | |
Tipologia | Articolo su rivista |
File in questo prodotto:
File | Descrizione | Tipologia | |
---|---|---|---|
Auto_Fluorescence_and_Histopathologic_Evaluation.20 (1).pdf | Versione dell'editore (versione pubblicata) | Administrator Richiedi una copia |
Pubblicazioni consigliate

I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris