We evaluated the impact of opioid substitution therapy (OST) on the completion, adherence, efficacy, and safety of the 3-direct-acting antiviral regimen of ombitasvir, paritaprevir (identified by AbbVie and Enanta) co-dosed with ritonavir, and dasabuvir ± ribavirin among patients infected with hepatitis C virus (HCV) genotype (GT) 1, with or without compensated cirrhosis.
Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in Patients With Chronic Hepatitis C Virus Genotype 1 Infection Receiving Opioid Substitution Therapy: A Post Hoc Analysis of 12 Clinical Trials / Grebely, J., Puoti, M., Wedemeyer, H., Cooper, C., Sulkowski, M.S., Foster, G.R., Berg, T., Villa, E., Rodriguez-Perez, F., Wyles, D.L., Schnell, G., Alami, N.N., Zhang, Z., Dumas, E., Dore, G.J.. - In: OPEN FORUM INFECTIOUS DISEASES. - ISSN 2328-8957. - 5:11(2018), pp. ofy248-ofy248. [10.1093/ofid/ofy248]
Efficacy and Safety of Ombitasvir/Paritaprevir/Ritonavir and Dasabuvir With or Without Ribavirin in Patients With Chronic Hepatitis C Virus Genotype 1 Infection Receiving Opioid Substitution Therapy: A Post Hoc Analysis of 12 Clinical Trials
Villa, Erica;
2018
Abstract
We evaluated the impact of opioid substitution therapy (OST) on the completion, adherence, efficacy, and safety of the 3-direct-acting antiviral regimen of ombitasvir, paritaprevir (identified by AbbVie and Enanta) co-dosed with ritonavir, and dasabuvir ± ribavirin among patients infected with hepatitis C virus (HCV) genotype (GT) 1, with or without compensated cirrhosis.| File | Dimensione | Formato | |
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ofy248.pdf
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