INTRODUCTION: Although differentiation between benign and malignant small renal tumors (≤4 cm) is still difficult, it is a demand for decision making and determining the treatment strategy. Our aim is to evaluate the role of multidetector row computed tomography (MDCT) in the differentiation of small renal clear cell carcinoma (RCC) and renal oncocytoma (RO).METHODS: We reviewed triphasic computed tomographic (CT) scans performed in 43 patients diagnosed with RCC (n = 23) and RO (n = 21). After an unenhanced CT phase of the upper abdomen, triple-phase acquisition included a cortico-medullary phase (CMP), a nephrographic phase (NP), and a pyelographic phase (PP), and lesions were evaluated both qualitatively and quantitatively.RESULTS: RCCs were hypervascular in 13 cases and hypovascular in 10 cases, while ROs were hypervascular in nine cases and hypovascular in 12 cases. Mean attenuation values (MAVs) for hypervascular RCCs and hypervascular ROs on unenhanced examination were 34.0 ± 7.1 and 31.3 ± 8.1 HU, respectively. Enhancement in CMP was 173.1 ± 45.2 HU for RCCs and 151.1 ± 36.0 HU for ROs and a gradual wash-out in NP (148.8 ± 34.3 and 137.1 ± 33.9 HU for RCCs and ROs, respectively) and in PP (98.2 ± 36.0 HU for RCCs and 79.4 ± 21.5 HU for ROs) was observed. MAV for hypovascular RCCs and hypovascular ROs on unenhanced examination were 32.4 ± 12.0 and 28.9 ± 8.0 HU, respectively. Both hypovascular RCCs and ROs showed a statistically significant difference in each post contrastographic phase.CONCLUSIONS: Absolute attenuation and the quantitative amount of the enhancement were not strong predictors for RO and RCC differentiation.

Value of triphasic MDCT in the differentiation of small renal cell carcinoma and oncocytoma / Scialpi, Michele; Martorana, Eugenio; Rondoni, Valeria; Eissa, Ahmed; Sherbiny, Ahmed El; Bevilacqua, Luigi; Ros, Luis H.; Escartín Martínez, Irene; Milizia, Michele; Manganaro, Lucia; Mazzei, Maria Antonietta; D'Andrea, Alfredo; Bianchi, Giampaolo. - In: UROLOGIA. - ISSN 1724-6075. - 84:4(2017), pp. 244-250. [10.5301/uj.5000256]

Value of triphasic MDCT in the differentiation of small renal cell carcinoma and oncocytoma

Martorana, Eugenio;Bevilacqua, Luigi;Bianchi, Giampaolo
2017

Abstract

INTRODUCTION: Although differentiation between benign and malignant small renal tumors (≤4 cm) is still difficult, it is a demand for decision making and determining the treatment strategy. Our aim is to evaluate the role of multidetector row computed tomography (MDCT) in the differentiation of small renal clear cell carcinoma (RCC) and renal oncocytoma (RO).METHODS: We reviewed triphasic computed tomographic (CT) scans performed in 43 patients diagnosed with RCC (n = 23) and RO (n = 21). After an unenhanced CT phase of the upper abdomen, triple-phase acquisition included a cortico-medullary phase (CMP), a nephrographic phase (NP), and a pyelographic phase (PP), and lesions were evaluated both qualitatively and quantitatively.RESULTS: RCCs were hypervascular in 13 cases and hypovascular in 10 cases, while ROs were hypervascular in nine cases and hypovascular in 12 cases. Mean attenuation values (MAVs) for hypervascular RCCs and hypervascular ROs on unenhanced examination were 34.0 ± 7.1 and 31.3 ± 8.1 HU, respectively. Enhancement in CMP was 173.1 ± 45.2 HU for RCCs and 151.1 ± 36.0 HU for ROs and a gradual wash-out in NP (148.8 ± 34.3 and 137.1 ± 33.9 HU for RCCs and ROs, respectively) and in PP (98.2 ± 36.0 HU for RCCs and 79.4 ± 21.5 HU for ROs) was observed. MAV for hypovascular RCCs and hypovascular ROs on unenhanced examination were 32.4 ± 12.0 and 28.9 ± 8.0 HU, respectively. Both hypovascular RCCs and ROs showed a statistically significant difference in each post contrastographic phase.CONCLUSIONS: Absolute attenuation and the quantitative amount of the enhancement were not strong predictors for RO and RCC differentiation.
84
4
244
250
Value of triphasic MDCT in the differentiation of small renal cell carcinoma and oncocytoma / Scialpi, Michele; Martorana, Eugenio; Rondoni, Valeria; Eissa, Ahmed; Sherbiny, Ahmed El; Bevilacqua, Luigi; Ros, Luis H.; Escartín Martínez, Irene; Milizia, Michele; Manganaro, Lucia; Mazzei, Maria Antonietta; D'Andrea, Alfredo; Bianchi, Giampaolo. - In: UROLOGIA. - ISSN 1724-6075. - 84:4(2017), pp. 244-250. [10.5301/uj.5000256]
Scialpi, Michele; Martorana, Eugenio; Rondoni, Valeria; Eissa, Ahmed; Sherbiny, Ahmed El; Bevilacqua, Luigi; Ros, Luis H.; Escartín Martínez, Irene; Milizia, Michele; Manganaro, Lucia; Mazzei, Maria Antonietta; D'Andrea, Alfredo; Bianchi, Giampaolo
File in questo prodotto:
File Dimensione Formato  
scialpi2017.pdf

non disponibili

Tipologia: Versione dell'editore (versione pubblicata)
Dimensione 355.85 kB
Formato Adobe PDF
355.85 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1166115
Citazioni
  • ???jsp.display-item.citation.pmc??? 1
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 5
social impact