In recent years, metabolomics has attracted great scientific attention. The metabolomics methodology might permit a view into transitional phases between healthy liver and nonalcoholic steatohepatitis. Metabolomics can help to analyze the metabolic alterations that play a main role in the progression of nonalcoholic steatohepatitis. Lipid, glucose, amino acid, and bile acid metabolism should be widely studied to understand the complex pathogenesis of nonalcoholic steatohepatitis. The discovery of new biomarkers would be important for diagnosis and staging of liver disease as well as for the assessment of efficacy of new drugs. Here, we review the metabolomics data regarding nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. We analyzed the main studies regarding the application of metabolomics methodology in the complex context of nonalcoholic steatohepatitis, trying to create a bridge from the basic to the clinical aspects.
Study of the Serum Metabolomic Profile in Nonalcoholic Fatty Liver Disease: Research and Clinical Perspectives / Gitto, Stefano; Schepis, Filippo; Andreone, Pietro; Villa, Erica. - In: METABOLITES. - ISSN 2218-1989. - 8:1(2018), pp. 17-17.
Data di pubblicazione: | 2018 |
Titolo: | Study of the Serum Metabolomic Profile in Nonalcoholic Fatty Liver Disease: Research and Clinical Perspectives |
Autore/i: | Gitto, Stefano; Schepis, Filippo; Andreone, Pietro; Villa, Erica |
Autore/i UNIMORE: | |
Digital Object Identifier (DOI): | http://dx.doi.org/10.3390/metabo8010017 |
Rivista: | |
Volume: | 8 |
Fascicolo: | 1 |
Pagina iniziale: | 17 |
Pagina finale: | 17 |
Codice identificativo ISI: | WOS:000442625700016 |
Codice identificativo Scopus: | 2-s2.0-85043769833 |
Codice identificativo Pubmed: | 29495258 |
Citazione: | Study of the Serum Metabolomic Profile in Nonalcoholic Fatty Liver Disease: Research and Clinical Perspectives / Gitto, Stefano; Schepis, Filippo; Andreone, Pietro; Villa, Erica. - In: METABOLITES. - ISSN 2218-1989. - 8:1(2018), pp. 17-17. |
Tipologia | Articolo su rivista |
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Gitto et al 2018 Metabolites.pdf | Versione dell'editore (versione pubblicata) | Open Access Visualizza/Apri |

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