Early initiation of combination antiretroviral therapy (cART), at higher CD4 cell counts, prevents disease progression and reduces sexual transmission of human immunodeficiency virus (HIV). We describe the temporal trends in CD4 cell counts at the start of cART in adults from low-income, lower-middle-income, upper-middle-income, and high-income countries (LICs, LMICs, UMICs, and HICs, respectively).
Global Trends in CD4 Cell Count at the Start of Antiretroviral Therapy: Collaborative Study of Treatment Programs / Anderegg, N; Panayidou, K; Abo, Y; Alejos, B; Althoff, Kn; Anastos, K; Antinori, A; Balestre, E; Becquet, R; Castagna, A; Castelnuovo, B; Chêne, G; Coelho, L; Collins, Ij; Costagliola, D; Crabtree-Ramírez, B; Dabis, F; d'Arminio Monforte, A; Davies, Ma; De Wit, S; Delpech, V; De La Mata, Nl; Duda, S; Freeman, A; Gange, Sj; Grabmeier-Pfistershammer, K; Gunsenheimer-Bartmeyer, B; Jiamsakul, A; Kitahata, Mm; Law, M; Manzardo, C; Mcgowan, C; Meyer, L; Moore, R; Mussini, C; Nakigoz, G; Nash, D; Tek Ng, O; Obel, N; Pantazis, N; Poda, A; Raben, D; Reiss, P; Riggen, L; Sabin, C; d'Amour Sinayobye, J; Sönnerborg, A; Stoeckle, M; Thorne, C; Torti, C; Twizere, C; Wasmuth, Jc; Wittkop, L; Wools-Kaloustian, K; Yotebieng, M; Kirk, O; Egger, M.. - In: CLINICAL INFECTIOUS DISEASES. - ISSN 1058-4838. - 66:6(2018), pp. 893-903. [10.1093/cid/cix915]
Global Trends in CD4 Cell Count at the Start of Antiretroviral Therapy: Collaborative Study of Treatment Programs
Mussini C;
2018
Abstract
Early initiation of combination antiretroviral therapy (cART), at higher CD4 cell counts, prevents disease progression and reduces sexual transmission of human immunodeficiency virus (HIV). We describe the temporal trends in CD4 cell counts at the start of cART in adults from low-income, lower-middle-income, upper-middle-income, and high-income countries (LICs, LMICs, UMICs, and HICs, respectively).
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