This chapter focuses on the identification of hepatocellular carcinoma (HCC) molecular signatures and the potentials of these signatures in prediction of HCC prognosis and driving of HCC therapeutic treatments. Progress in molecular profiling studies using DNA-microarray-based gene expression profiling has provided new insight about HCC pathogenesis, and gene signatures that can distinguish tumor subtypes assist clinical staging and predict patient outcomes. This provides the possibility to improve the stratification of HCC patients at a molecular level and, in the near future, will be potential in paving the way for tailored medicine in HCC patients.

Biology of hepatocellular carcinoma / Critelli, Rosina Maria; De Maria, Nicola; Villa, Erica. - In: DIGESTIVE DISEASES. - ISSN 0257-2753. - 33:5(2015), pp. 635-641. [10.1159/000438472]

Biology of hepatocellular carcinoma

Critelli, Rosina Maria;Villa, Erica
2015-01-01

Abstract

This chapter focuses on the identification of hepatocellular carcinoma (HCC) molecular signatures and the potentials of these signatures in prediction of HCC prognosis and driving of HCC therapeutic treatments. Progress in molecular profiling studies using DNA-microarray-based gene expression profiling has provided new insight about HCC pathogenesis, and gene signatures that can distinguish tumor subtypes assist clinical staging and predict patient outcomes. This provides the possibility to improve the stratification of HCC patients at a molecular level and, in the near future, will be potential in paving the way for tailored medicine in HCC patients.
23-set-2015
33
5
635
641
Biology of hepatocellular carcinoma / Critelli, Rosina Maria; De Maria, Nicola; Villa, Erica. - In: DIGESTIVE DISEASES. - ISSN 0257-2753. - 33:5(2015), pp. 635-641. [10.1159/000438472]
Critelli, Rosina Maria; De Maria, Nicola; Villa, Erica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1154647
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