The main stages of cirrhosis (compensated and decompensated) have been substaged based on clinical, endoscopic, and portal pressure (determined by the hepatic venous pressure gradient, HVPG) features. Vasodilatation leading to a hyperdynamic circulatory state is central in the development of a late decompensated stage with inflammation being currently considered a key driver. We aimed to assess hepatic/systemic hemodynamics and inflammation (by C reactive protein, CRP) among the different substages of cirrhosis and to investigate their interrelationship and prognostic relevance.

Cardiopulmonary hemodynamics and c-reactive protein as prognostic indicators in compensated and decompensated cirrhosis / Turco, Laura; Garcia-Tsao, Guadalupe; Magnani, Ilenia; Bianchini, Marcello; Costetti, Martina; Caporali, Cristian; Colopi, Stefano; Simonini, Emilio; De Maria, Nicola; Banchelli, Federico; Rossi, Rosario; Villa, Erica; Schepis, Filippo. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 68:5(2018), pp. 949-958. [10.1016/j.jhep.2017.12.027]

Cardiopulmonary hemodynamics and c-reactive protein as prognostic indicators in compensated and decompensated cirrhosis

Turco, Laura;MAGNANI, ILENIA;Bianchini, Marcello;Simonini, Emilio;Rossi, Rosario;Villa, Erica;Schepis, Filippo
2018

Abstract

The main stages of cirrhosis (compensated and decompensated) have been substaged based on clinical, endoscopic, and portal pressure (determined by the hepatic venous pressure gradient, HVPG) features. Vasodilatation leading to a hyperdynamic circulatory state is central in the development of a late decompensated stage with inflammation being currently considered a key driver. We aimed to assess hepatic/systemic hemodynamics and inflammation (by C reactive protein, CRP) among the different substages of cirrhosis and to investigate their interrelationship and prognostic relevance.
2018
10-gen-2018
68
5
949
958
Cardiopulmonary hemodynamics and c-reactive protein as prognostic indicators in compensated and decompensated cirrhosis / Turco, Laura; Garcia-Tsao, Guadalupe; Magnani, Ilenia; Bianchini, Marcello; Costetti, Martina; Caporali, Cristian; Colopi, Stefano; Simonini, Emilio; De Maria, Nicola; Banchelli, Federico; Rossi, Rosario; Villa, Erica; Schepis, Filippo. - In: JOURNAL OF HEPATOLOGY. - ISSN 0168-8278. - 68:5(2018), pp. 949-958. [10.1016/j.jhep.2017.12.027]
Turco, Laura; Garcia-Tsao, Guadalupe; Magnani, Ilenia; Bianchini, Marcello; Costetti, Martina; Caporali, Cristian; Colopi, Stefano; Simonini, Emilio; De Maria, Nicola; Banchelli, Federico; Rossi, Rosario; Villa, Erica; Schepis, Filippo
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1154103
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