A rapid and simple HPLC method is described for the separation and quantitative determination of bronidox and bronopol used as preservatives and listed in the current EEC Council Directives on cosmetic products. The proposed method allows the routine detection of these preservatives in different cosmetic formulations with a view for verifying their complicance with Italian legislation.
DETERMINATION OF BRONIDOX AND BRONOPOL IN COSMETIC PRODUCTS BY REVERSED PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY / Ferioli, Valeria; Vezzalini, Francesca; Rustichelli, Cecilia; Gamberini, G.. - In: IL FARMACO. - ISSN 0014-827X. - ELETTRONICO. - 47:(1992), pp. 833-839.