To study the causes of residual posttransfusion hepatitis, serum from implicated donors was tested by PCR for the presence of HCV RNA. Of 20 anti HCV negative donors, 4 were HCV RNA positive and thus, infective. The results suggest that higher-level investigations are necessary for prospective donors who present blood enzyme abnormalities or other questionable characteristics.
PRESENCE OF HCV RNA IN SERUM OF ASYMPTOMATIC BLOOD-DONORS INVOLVED IN POSTTRANSFUSION HEPATITIS (PTH) / Villa, Erica; Melegari, M; Ferretti, Ilva; Vecchi, C; Scaglioni, Pp; Depalma, M; Manenti, Federico. - In: ARCHIVES OF VIROLOGY. - ISSN 0304-8608. - STAMPA. - 4:(1992), pp. 247-248.
PRESENCE OF HCV RNA IN SERUM OF ASYMPTOMATIC BLOOD-DONORS INVOLVED IN POSTTRANSFUSION HEPATITIS (PTH)
VILLA, Erica;FERRETTI, Ilva;MANENTI, Federico
1992
Abstract
To study the causes of residual posttransfusion hepatitis, serum from implicated donors was tested by PCR for the presence of HCV RNA. Of 20 anti HCV negative donors, 4 were HCV RNA positive and thus, infective. The results suggest that higher-level investigations are necessary for prospective donors who present blood enzyme abnormalities or other questionable characteristics.
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