Over the last few years, BRAF has emerged as a validated target in melanoma. This review summarises recent advances in the development of BRAF inhibitors, focussing on agents that have been assessed clinically. © 2011 Elsevier Ltd. All rights reserved.
Small molecule inhibitors of BRAF in clinical trials / Zambon, Alfonso; Niculescu Duvaz, Ion; Niculescu Duvaz, Dan; Marais, Richard; Springer, Caroline J.. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 22:2(2012), pp. 789-792. [10.1016/j.bmcl.2011.11.060]
Small molecule inhibitors of BRAF in clinical trials
ZAMBON, Alfonso;
2012
Abstract
Over the last few years, BRAF has emerged as a validated target in melanoma. This review summarises recent advances in the development of BRAF inhibitors, focussing on agents that have been assessed clinically. © 2011 Elsevier Ltd. All rights reserved.
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