OBJECTIVE: The aim of the study was to identify the main aspects involved in patient selection, the choice of therapeutic agents and the safety profile, as well as the medico-legal and organizational aspects of intra-articular injection therapies for osteoarthritis.METHODS: A committee of 10 experts from Italian universities, public hospitals, territorial services, research institutes and patient associations was set up. Fifty-two clinicians from a large number of Italian medical centers specialized in intra-articular injection therapy took part in a Delphi process aimed at obtaining consensus statements among the participants.RESULTS: Large consensus was obtained for statements grouped under the following main themes: treatment indications; drug/medical device choice; treatment efficacy; and appropriate setting.CONCLUSIONS: The consensus statements developed by a large number of experts may be used as a practical reference tool to help physicians treat osteoarthritis patients by means of intra-articular injection therapies.

Appropriateness of clinical and organizational criteria for intra-articular injection therapies in osteoarthritis. A Delphi method consensus initiative among experts in Italy / Paoloni, Marco; Bernetti, Andrea; Belelli, Alberto; Brignoli, Ovidio; Buoso, Sandro; Caputi, Achille Patrizio; Catani, Fabio; Coclite, Daniela; Fini, Massimo; Mantovani, Lorenzo; Migliore, Alberto; Napoletano, Antonello; Viora, Ugo; Santilli, Valter. - In: ANNALI DELL'ISTITUTO SUPERIORE DI SANITÀ. - ISSN 0021-2571. - 51:2(2015), pp. 131-138.

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