Previous studies have shown conflicting results about safety of surgical lung biopsy (SLB) in usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis (IPF) patients. Study design: we performed a retrospective analysis of all patients who underwent SLB between 2003 and 2013 at the University Hospital of Modena (Italy), to assess morbidity and mortality among patients with UIP/IPF , as compared to patients with other diffuse parenchymal lung diseases (non UIP/IPF). Results: we analyzed 73 patients with (n=29) and without (n=44) UIP/IPF, in which medical history, histology, and survival status were collected. UIP/IPF was diagnosed according to international guidelines. In 59 patients lung biopsy was performed via video-assisted thoracoscopy; in 14 patients thoracotomy was conducted. No intraoperative complications were observed. Postoperative complications were not significantly different between groups and consisted of fever (n=1 in UIP/IPF group; n=4 in non-UIP/IPF group), pneumothorax (n=1 in non-UIP/IPF), pleural effusion (n=1 in non-UIP/IPF), and acute exacerbation (n=1 in both groups, who died). There was no 30-day, 60-day and 90-day mortality. Conclusions: we conclude that surgical lung biopsy can be safely performed in patients with suspected UIP/IPF.
|Data di pubblicazione:||2015|
|Titolo:||Morbidity and Mortality in Patients with Idiopathic Pulmonary Fibrosis Undergoing Diagnostic Surgical Lung Biopsy|
|Autore/i:||Cerri, Stefania; Sghedoni, Enrico; Montanari, Gloria; Taddei, Sofia; Aramini, Beatrice; Zelent, Gabriele; Rossi, Giulio; Stefani, Alessandro; Torricelli, Pietro; Morandi, Uliano; Luppi, Fabrizio|
|Rivista:||AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE|
|Citazione:||Morbidity and Mortality in Patients with Idiopathic Pulmonary Fibrosis Undergoing Diagnostic Surgical Lung Biopsy / Cerri, Stefania; Sghedoni, Enrico; Montanari, Gloria; Taddei, Sofia; Aramini, Beatrice; Zelent, Gabriele; Rossi, Giulio; Stefani, Alessandro; Torricelli, Pietro; Morandi, Uliano; Luppi, Fabrizio. - In: AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. - ISSN 1073-449X. - 191(2015), p. A3035. ((Intervento presentato al convegno American Thoracic Society 2015 International Conference tenutosi a Denver, Colorado (USA) nel May 15-20.|
|Tipologia||Abstract in Rivista|
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