We demonstrate an electrolyte-gated hybrid nanoparticle/organic synapstor (synapse-transistor, termed EGOS) that exhibits short-term plasticity as biological synapses. The response of EGOS makes it suitable to be interfaced with neurons: short-term plasticity is observed at spike voltage as low as 50 mV (in a par with the amplitude of action potential in neurons) and with a typical response time in the range of tens milliseconds. Human neuroblastoma stem cells are adhered and differentiated into neurons on top of EGOS. We observe that the presence of the cells does not alter short-term plasticity of the device.

Electrolyte-gated organic synapse transistor interfaced with neurons / Desbief, Simon; DI LAURO, Michele; Casalini, Stefano; Guerin, David; Tortorella, Silvia; Barbalinardo, Marianna; Kyndiah, Adrica; Murgia, Mauro; Cramer, Tobias; Biscarini, Fabio; Vuillaume, Dominique. - In: ORGANIC ELECTRONICS. - ISSN 1566-1199. - 38:(2016), pp. 21-28. [10.1016/j.orgel.2016.07.028]

Electrolyte-gated organic synapse transistor interfaced with neurons

DI LAURO, MICHELE;CASALINI, Stefano;Murgia, Mauro;BISCARINI, FABIO;
2016

Abstract

We demonstrate an electrolyte-gated hybrid nanoparticle/organic synapstor (synapse-transistor, termed EGOS) that exhibits short-term plasticity as biological synapses. The response of EGOS makes it suitable to be interfaced with neurons: short-term plasticity is observed at spike voltage as low as 50 mV (in a par with the amplitude of action potential in neurons) and with a typical response time in the range of tens milliseconds. Human neuroblastoma stem cells are adhered and differentiated into neurons on top of EGOS. We observe that the presence of the cells does not alter short-term plasticity of the device.
2016
38
21
28
Electrolyte-gated organic synapse transistor interfaced with neurons / Desbief, Simon; DI LAURO, Michele; Casalini, Stefano; Guerin, David; Tortorella, Silvia; Barbalinardo, Marianna; Kyndiah, Adrica; Murgia, Mauro; Cramer, Tobias; Biscarini, Fabio; Vuillaume, Dominique. - In: ORGANIC ELECTRONICS. - ISSN 1566-1199. - 38:(2016), pp. 21-28. [10.1016/j.orgel.2016.07.028]
Desbief, Simon; DI LAURO, Michele; Casalini, Stefano; Guerin, David; Tortorella, Silvia; Barbalinardo, Marianna; Kyndiah, Adrica; Murgia, Mauro; Crame...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1136555
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