The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported.

AISF position paper on liver disease and pregnancy / Morisco, Filomena; Bruno, Raffaele; Bugianesi, Elisabetta; Burra, Patrizia; Calvaruso, Vincenza; Cannoni, Alice; Caporaso, Nicola; Caviglia, Gian Paolo; Ciancio, Alessia; Fargion, Silvia; Federico, Alessandro; Floreani, Annarosa; Gaeta, Giovanni Battista; Guarino, Maria; Invernizzi, Pietro; Licata, Anna; Loguercio, Carmela; Mazzella, Giuseppe; Petraglia, Felice; Primignani, Massimo; Rodriguez Castro, Kryssia; Smedile, Antonina; Valenti, Luca; Vanni, Ester; Vannuccini, Silvia; Voltolini, Chiara; Villa, Erica; Italian Assoc Study Liver, Aisf. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 48:(2016), pp. 120-137. [10.1016/j.dld.2015.11.004]

AISF position paper on liver disease and pregnancy

VILLA, Erica;
2016

Abstract

The relationship between liver disease and pregnancy is of great clinical impact. Severe liver disease in pregnancy is rare; however, pregnancy-related liver disease is the most frequent cause of liver dysfunction during pregnancy and represents a severe threat to foetal and maternal survival. A rapid differential diagnosis between liver disease related or unrelated to pregnancy is required in women who present with liver dysfunction during pregnancy. This report summarizes the recommendation of an expert panel established by the Italian Association for the Study of the Liver (AISF) on the management of liver disease during pregnancy. The article provides an overview of liver disease occurring in pregnancy, an update on the key mechanisms involved in its pathogenesis, and an assessment of the available treatment options. The report contains in three sections: (1) specific liver diseases of pregnancy; (2) liver disease occurring during pregnancy; and (3) pregnancy in patients with pre-existing chronic liver disease. Each topic is discussed considering the most relevant data available in literature; the final statements are formulated according to both scientific evidence and clinical expertise of the involved physicians, and the AISF expert panel recommendations are reported.
14-nov-2015
48
120
137
AISF position paper on liver disease and pregnancy / Morisco, Filomena; Bruno, Raffaele; Bugianesi, Elisabetta; Burra, Patrizia; Calvaruso, Vincenza; Cannoni, Alice; Caporaso, Nicola; Caviglia, Gian Paolo; Ciancio, Alessia; Fargion, Silvia; Federico, Alessandro; Floreani, Annarosa; Gaeta, Giovanni Battista; Guarino, Maria; Invernizzi, Pietro; Licata, Anna; Loguercio, Carmela; Mazzella, Giuseppe; Petraglia, Felice; Primignani, Massimo; Rodriguez Castro, Kryssia; Smedile, Antonina; Valenti, Luca; Vanni, Ester; Vannuccini, Silvia; Voltolini, Chiara; Villa, Erica; Italian Assoc Study Liver, Aisf. - In: DIGESTIVE AND LIVER DISEASE. - ISSN 1590-8658. - 48:(2016), pp. 120-137. [10.1016/j.dld.2015.11.004]
Morisco, Filomena; Bruno, Raffaele; Bugianesi, Elisabetta; Burra, Patrizia; Calvaruso, Vincenza; Cannoni, Alice; Caporaso, Nicola; Caviglia, Gian Paolo; Ciancio, Alessia; Fargion, Silvia; Federico, Alessandro; Floreani, Annarosa; Gaeta, Giovanni Battista; Guarino, Maria; Invernizzi, Pietro; Licata, Anna; Loguercio, Carmela; Mazzella, Giuseppe; Petraglia, Felice; Primignani, Massimo; Rodriguez Castro, Kryssia; Smedile, Antonina; Valenti, Luca; Vanni, Ester; Vannuccini, Silvia; Voltolini, Chiara; Villa, Erica; Italian Assoc Study Liver, Aisf
File in questo prodotto:
File Dimensione Formato  
1-s2.0-S1590865815006921-main.pdf

non disponibili

Tipologia: Versione dell'editore (versione pubblicata)
Dimensione 649.09 kB
Formato Adobe PDF
649.09 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1133346
Citazioni
  • ???jsp.display-item.citation.pmc??? 6
  • Scopus 25
  • ???jsp.display-item.citation.isi??? 19
social impact