We report a case of primary large cell neuroendocrine carcinoma of the renal pelvis, diagnosed in a 79-year-old man. The abdominal computed tomography showed a solid, vegetant lesion in the left renal pelvis, conditioning marked hydronephrosis. The patient underwent radical nephroureterectomy. The histological examination showed a large cell neuroendocrine carcinoma associated with a high-grade urothelial carcinoma, with local invasion (pT3). Large cell renal neuroendocrine carcinomas are rare tumors with an aggressive course and a bad prognosis. At present, only five cases were reported in literature.
Primary large cell neuroendocrine carcinoma of the renal pelvis : a case report / C., Palumbo; M., Talso; P. G., Dell'Orto; G., Cozzi; E., De Lorenzis; A., Conti; M., Maggioni; Rocco, Bernardo Maria Cesare; A., Maggioni; F., Rocco. - In: UROLOGIA. - ISSN 0391-5603. - 81:1(2014), pp. 57-59. [10.5301/urologia.5000033]
Primary large cell neuroendocrine carcinoma of the renal pelvis : a case report
ROCCO, Bernardo Maria Cesare;
2014
Abstract
We report a case of primary large cell neuroendocrine carcinoma of the renal pelvis, diagnosed in a 79-year-old man. The abdominal computed tomography showed a solid, vegetant lesion in the left renal pelvis, conditioning marked hydronephrosis. The patient underwent radical nephroureterectomy. The histological examination showed a large cell neuroendocrine carcinoma associated with a high-grade urothelial carcinoma, with local invasion (pT3). Large cell renal neuroendocrine carcinomas are rare tumors with an aggressive course and a bad prognosis. At present, only five cases were reported in literature.
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