The onset of obsessive-compulsive disorder (OCD) after age 50 is rare and generally related to an organic etiology. An involvement of fronto-striatal circuits has been strongly suggested, whereas cerebellum remains so far scarcely explored. We present here the description of a "pure" late-onset OCD associated with a cerebellar lesion, neither comorbid with other mental disorders nor with neurological syndromes. To our knowledge, this condition was not previously described in literature. The patient is a 62-year-old woman who developed a late-onset OCD associated with a left cerebellar lesion due to an arachnoid cyst in the left posterior fossa. We debate the possible role of the cerebellar lesion in favoring a transition from a predisposing liability (namely an obsessive-compulsive personality disorder and a depressive status) to the onset of OCD in this woman. © 2014 Springer Science+Business Media.

Late-onset obsessive-compulsive disorder associated with left cerebellar lesion / Tonna, Matteo; Ottoni, Rebecca; Ossola, Paolo; De Panfilis, Chiara; Marchesi, Carlo. - In: THE CEREBELLUM. - ISSN 1473-4222. - 13:4(2014), pp. 531-535. [10.1007/s12311-014-0561-8]

Late-onset obsessive-compulsive disorder associated with left cerebellar lesion

TONNA, MATTEO;
2014

Abstract

The onset of obsessive-compulsive disorder (OCD) after age 50 is rare and generally related to an organic etiology. An involvement of fronto-striatal circuits has been strongly suggested, whereas cerebellum remains so far scarcely explored. We present here the description of a "pure" late-onset OCD associated with a cerebellar lesion, neither comorbid with other mental disorders nor with neurological syndromes. To our knowledge, this condition was not previously described in literature. The patient is a 62-year-old woman who developed a late-onset OCD associated with a left cerebellar lesion due to an arachnoid cyst in the left posterior fossa. We debate the possible role of the cerebellar lesion in favoring a transition from a predisposing liability (namely an obsessive-compulsive personality disorder and a depressive status) to the onset of OCD in this woman. © 2014 Springer Science+Business Media.
2014
13
4
531
535
Late-onset obsessive-compulsive disorder associated with left cerebellar lesion / Tonna, Matteo; Ottoni, Rebecca; Ossola, Paolo; De Panfilis, Chiara; Marchesi, Carlo. - In: THE CEREBELLUM. - ISSN 1473-4222. - 13:4(2014), pp. 531-535. [10.1007/s12311-014-0561-8]
Tonna, Matteo; Ottoni, Rebecca; Ossola, Paolo; De Panfilis, Chiara; Marchesi, Carlo
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1120769
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