Background: Early treatment for infertile women with polycystic ovary syndrome (PCOS) is likely crucial and includes mainly clomiphene citrate (CC) and metformin.Objectives: To review the literature data regarding the use of CC, metformin, or both for the treatment of infertility in anovulatory patients with PCOS.Materials and Methods: Using PubMed database, all main relevant articles studying therapy naïve patients with PCOS who received CC, metformin or both were searched, reviewed and analyzed.Main Results and Conclusions: In infertile obese PCOS patients, CC is the therapy of choice for inducing ovulation. Combining CC and metformin is not more effective than CC alone. Further studies are needed to define the best first line treatment in non-obese PCOS patients. © 2013 Bentham Science.

Clomiphene citrate, metformin or both for ovulation induction in therapy naïve women with polycystic ovary syndrome (PCOS)? A descriptive review / Palomba, Stefano; Falbo, Angela; LA SALA, Giovanni Battista. - In: CURRENT DRUG THERAPY. - ISSN 1574-8855. - 8:1(2013), pp. 30-37. [10.2174/1574885511308010004]

Clomiphene citrate, metformin or both for ovulation induction in therapy naïve women with polycystic ovary syndrome (PCOS)? A descriptive review

Palomba, Stefano;LA SALA, Giovanni Battista
2013

Abstract

Background: Early treatment for infertile women with polycystic ovary syndrome (PCOS) is likely crucial and includes mainly clomiphene citrate (CC) and metformin.Objectives: To review the literature data regarding the use of CC, metformin, or both for the treatment of infertility in anovulatory patients with PCOS.Materials and Methods: Using PubMed database, all main relevant articles studying therapy naïve patients with PCOS who received CC, metformin or both were searched, reviewed and analyzed.Main Results and Conclusions: In infertile obese PCOS patients, CC is the therapy of choice for inducing ovulation. Combining CC and metformin is not more effective than CC alone. Further studies are needed to define the best first line treatment in non-obese PCOS patients. © 2013 Bentham Science.
2013
8
1
30
37
Clomiphene citrate, metformin or both for ovulation induction in therapy naïve women with polycystic ovary syndrome (PCOS)? A descriptive review / Palomba, Stefano; Falbo, Angela; LA SALA, Giovanni Battista. - In: CURRENT DRUG THERAPY. - ISSN 1574-8855. - 8:1(2013), pp. 30-37. [10.2174/1574885511308010004]
Palomba, Stefano; Falbo, Angela; LA SALA, Giovanni Battista
File in questo prodotto:
File Dimensione Formato  
Palomba S 2013 Curr Drug Therapy.pdf

Accesso riservato

Tipologia: Versione pubblicata dall'editore
Dimensione 401.65 kB
Formato Adobe PDF
401.65 kB Adobe PDF   Visualizza/Apri   Richiedi una copia
Pubblicazioni consigliate

Licenza Creative Commons
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1118269
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 1
  • ???jsp.display-item.citation.isi??? ND
social impact