The pK(a) values of adenine N1 and cytosine N3 in the non-self complementary title compounds have been measured by C-13 NMR, using an inverse probe. in the deoxydinucleotide adenine N1 has pK(a) = 2.52, markedly smaller than that of cytosine N3 for which pK(a) = 4.42. In the hexanucleotide the pK(a) values of adenine N1 and cytosine N3 are much closer, being 3.97 and 4.67, respectively.
PKA DETERMINATION OF THE DEOXYDINUCLEOTIDE MONOPHOSPHATE CA AND OF THE CORRESPONDING HEXANUCLEOTIDE CACACA BY INVERSE-DETECTED C-13 NMR / Barbarella, G; Schenetti, Luisa; Tondelli, L.. - In: GAZZETTA CHIMICA ITALIANA. - ISSN 0016-5603. - STAMPA. - 123:(1993), pp. 251-255.
PKA DETERMINATION OF THE DEOXYDINUCLEOTIDE MONOPHOSPHATE CA AND OF THE CORRESPONDING HEXANUCLEOTIDE CACACA BY INVERSE-DETECTED C-13 NMR
SCHENETTI, Luisa;
1993
Abstract
The pK(a) values of adenine N1 and cytosine N3 in the non-self complementary title compounds have been measured by C-13 NMR, using an inverse probe. in the deoxydinucleotide adenine N1 has pK(a) = 2.52, markedly smaller than that of cytosine N3 for which pK(a) = 4.42. In the hexanucleotide the pK(a) values of adenine N1 and cytosine N3 are much closer, being 3.97 and 4.67, respectively.
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris
