Brimonidine is a selective α2 adrenergic receptor agonist with potent vasoconstrictive activity topically used for treatment of facial flushing and erythema caused by rosacea. Direct evidence for the in vivo morphology changes in skin vessels induced by topical application of brimonidine is limited. Dynamic optical coherence tomography is a novel technology that combines conventional OCT with information on flow and thereby provides supplementary information about the microvasculature. Dynamic OCT is non-invasive and creates high-resolution in vivo images of skin to a depth of maximum 2 mm.

In vivo, micro-morphological vascular changes induced by topical brimonidine studied by Dynamic optical coherence tomography / Themstrup, L; Ciardo, Silvia; Manfredi, Marco; Ulrich, M; Pellacani, Giovanni; Welzel, J; Jemec, G. B. E.. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 1468-3083. - ELETTRONICO. - 30:(2016), pp. 974-979. [10.1111/jdv.13596]

In vivo, micro-morphological vascular changes induced by topical brimonidine studied by Dynamic optical coherence tomography

CIARDO, SILVIA;MANFREDI, MARCO;PELLACANI, Giovanni;
2016

Abstract

Brimonidine is a selective α2 adrenergic receptor agonist with potent vasoconstrictive activity topically used for treatment of facial flushing and erythema caused by rosacea. Direct evidence for the in vivo morphology changes in skin vessels induced by topical application of brimonidine is limited. Dynamic optical coherence tomography is a novel technology that combines conventional OCT with information on flow and thereby provides supplementary information about the microvasculature. Dynamic OCT is non-invasive and creates high-resolution in vivo images of skin to a depth of maximum 2 mm.
25-feb-2016
30
974
979
In vivo, micro-morphological vascular changes induced by topical brimonidine studied by Dynamic optical coherence tomography / Themstrup, L; Ciardo, Silvia; Manfredi, Marco; Ulrich, M; Pellacani, Giovanni; Welzel, J; Jemec, G. B. E.. - In: JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY. - ISSN 1468-3083. - ELETTRONICO. - 30:(2016), pp. 974-979. [10.1111/jdv.13596]
Themstrup, L; Ciardo, Silvia; Manfredi, Marco; Ulrich, M; Pellacani, Giovanni; Welzel, J; Jemec, G. B. E.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11380/1107864
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