Randomized controlled trials have generated strong evidence on the efficacy of electrical device therapy in selected patients with heart failure (HF). The enrolment criteria of these three trials generated patient profiles that helped to shape current guidelines on chronic heart failure (CHF) treatment and sudden cardiac death (SCD) prevention. We investigated the prevalence of trial-generated profiles for implantable defibrillator or cardiac resynchronization therapy candidacy among HF outpatients; we explored differences between real-world and trial populations and we evaluated 1-year survival without device treatment.
Trial-generated profiles for implantation of electrical devices in outpatients with heart failure: real-world prevalence and 1-year outcome / Boriani, Giuseppe; Rapezzi, C; Diemberger, I; Gonzini, L; Gorini, M; cci D, L. u.; Sinagra, G; Cooke, Rm; Di Pasquale, G; Tavazzi, L; Maggioni, Ap. - In: JOURNAL OF EVALUATION IN CLINICAL PRACTICE. - ISSN 1356-1294. - 16:1(2010), pp. 82-91. [10.1111/j.1365-2753.2008.01118.x]
Trial-generated profiles for implantation of electrical devices in outpatients with heart failure: real-world prevalence and 1-year outcome.
BORIANI, Giuseppe;
2010
Abstract
Randomized controlled trials have generated strong evidence on the efficacy of electrical device therapy in selected patients with heart failure (HF). The enrolment criteria of these three trials generated patient profiles that helped to shape current guidelines on chronic heart failure (CHF) treatment and sudden cardiac death (SCD) prevention. We investigated the prevalence of trial-generated profiles for implantable defibrillator or cardiac resynchronization therapy candidacy among HF outpatients; we explored differences between real-world and trial populations and we evaluated 1-year survival without device treatment.
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