Simple enucleation versus standard partial nephrectomy for clinical T1 renal masses: perioperative outcomes based on a matched-pair comparison of 396 patients (RECORd project). Longo N1, Minervini A2, Antonelli A3, Bianchi G4, Bocciardi AM5, Cunico SC3, Fiori C6, Fusco F7, Giancane S2, Mari A2, Martorana G8, Mirone V1, Morgia G9, Novara G10, Porpiglia F6, Raspollini MR11, Rocco F12, Rovereto B13, Schiavina R8, Serni S2, Simeone C3, Verze P1, Volpe A14, Ficarra V10, Carini M2. Author information Abstract OBJECTIVES: To compare simple enucleation (SE) and standard partial nephrectomy (SPN) in terms of surgical results in a multicenter dataset (RECORd Project). MATERIALS AND METHODS: patients treated with nephron sparing surgery (NSS) for clinical T1 renal tumors between January 2009 and January 2011 were evaluated. Overall, 198 patients who underwent SE were retrospectively matched to 198 patients who underwent SPN. The SPN and SE groups were compared regarding intraoperative, early post-operative and pathologic outcome variables. Multivariable analysis was applied to analyze predictors of positive surgical margin (PSM) status. RESULTS: SE was associated with similar WIT (18 vs 17.8 min), lower intraoperative blood loss (177 vs 221 cc, p = 0.02) and shorter operative time (121 vs 147 min; p < 0.0001). Surgical approach (laparoscopic vs. open), tumor size and type of indication (elective/relative vs absolute) were associated with WIT >20 min. The incidence of PSM was significantly lower in patients treated with SE (1.4% vs 6.9%; p = 0.02). At multivariable analysis, PSM was related to the surgical technique, with a 4.7-fold increased risk of PSM for SPN compared to SE. The incidence of overall, medical and surgical complications was similar between SE and SPN. CONCLUSIONS: Type of NSS technique (SE vs SPN) adopted has a negligible impact on WIT and postoperative morbidity but SE seems protective against PSM occurrence. Copyright © 2014 Elsevier Ltd. All rights reserved.

Simple enucleation versus standard partial nephrectomy for clinical T1 renal masses: Perioperative outcomes based on a matched-pair comparison of 396 patients (RECORd project) / Longo, N.; Minervini, A.; Antonelli, A.; Bianchi, Giampaolo; Bocciardi, A. M.; Cunico, S. C.; Fiori, Chiara; Fusco, F; Giancane, S.; Mari, A.; Martorana, G.; Mirone, V.; Morgia, G.; Novara, G.; Porpiglia, F.; Raspollini, M. R.; Rocco, F.; Rovereto, B.; Schiavina, R.; Serni, S.; Simeone, Carmine; Verze, P.; Volpe, Annibale; Ficarra, V.; Carini, Marina. - In: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0748-7983. - 40:(2014), pp. 762-768. [10.1016/j.ejso.2014.01.007]

Simple enucleation versus standard partial nephrectomy for clinical T1 renal masses: Perioperative outcomes based on a matched-pair comparison of 396 patients (RECORd project)

BIANCHI, Giampaolo;Fiori, Chiara;SIMEONE, CARMINE;VOLPE, Annibale;CARINI, MARINA
2014

Abstract

Simple enucleation versus standard partial nephrectomy for clinical T1 renal masses: perioperative outcomes based on a matched-pair comparison of 396 patients (RECORd project). Longo N1, Minervini A2, Antonelli A3, Bianchi G4, Bocciardi AM5, Cunico SC3, Fiori C6, Fusco F7, Giancane S2, Mari A2, Martorana G8, Mirone V1, Morgia G9, Novara G10, Porpiglia F6, Raspollini MR11, Rocco F12, Rovereto B13, Schiavina R8, Serni S2, Simeone C3, Verze P1, Volpe A14, Ficarra V10, Carini M2. Author information Abstract OBJECTIVES: To compare simple enucleation (SE) and standard partial nephrectomy (SPN) in terms of surgical results in a multicenter dataset (RECORd Project). MATERIALS AND METHODS: patients treated with nephron sparing surgery (NSS) for clinical T1 renal tumors between January 2009 and January 2011 were evaluated. Overall, 198 patients who underwent SE were retrospectively matched to 198 patients who underwent SPN. The SPN and SE groups were compared regarding intraoperative, early post-operative and pathologic outcome variables. Multivariable analysis was applied to analyze predictors of positive surgical margin (PSM) status. RESULTS: SE was associated with similar WIT (18 vs 17.8 min), lower intraoperative blood loss (177 vs 221 cc, p = 0.02) and shorter operative time (121 vs 147 min; p < 0.0001). Surgical approach (laparoscopic vs. open), tumor size and type of indication (elective/relative vs absolute) were associated with WIT >20 min. The incidence of PSM was significantly lower in patients treated with SE (1.4% vs 6.9%; p = 0.02). At multivariable analysis, PSM was related to the surgical technique, with a 4.7-fold increased risk of PSM for SPN compared to SE. The incidence of overall, medical and surgical complications was similar between SE and SPN. CONCLUSIONS: Type of NSS technique (SE vs SPN) adopted has a negligible impact on WIT and postoperative morbidity but SE seems protective against PSM occurrence. Copyright © 2014 Elsevier Ltd. All rights reserved.
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Simple enucleation versus standard partial nephrectomy for clinical T1 renal masses: Perioperative outcomes based on a matched-pair comparison of 396 patients (RECORd project) / Longo, N.; Minervini, A.; Antonelli, A.; Bianchi, Giampaolo; Bocciardi, A. M.; Cunico, S. C.; Fiori, Chiara; Fusco, F; Giancane, S.; Mari, A.; Martorana, G.; Mirone, V.; Morgia, G.; Novara, G.; Porpiglia, F.; Raspollini, M. R.; Rocco, F.; Rovereto, B.; Schiavina, R.; Serni, S.; Simeone, Carmine; Verze, P.; Volpe, Annibale; Ficarra, V.; Carini, Marina. - In: EUROPEAN JOURNAL OF SURGICAL ONCOLOGY. - ISSN 0748-7983. - 40:(2014), pp. 762-768. [10.1016/j.ejso.2014.01.007]
Longo, N.; Minervini, A.; Antonelli, A.; Bianchi, Giampaolo; Bocciardi, A. M.; Cunico, S. C.; Fiori, Chiara; Fusco, F; Giancane, S.; Mari, A.; Martorana, G.; Mirone, V.; Morgia, G.; Novara, G.; Porpiglia, F.; Raspollini, M. R.; Rocco, F.; Rovereto, B.; Schiavina, R.; Serni, S.; Simeone, Carmine; Verze, P.; Volpe, Annibale; Ficarra, V.; Carini, Marina
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