Novel drugs targeting TNF-alpha are available for treatment of RA. Fibroblast-like synoviocytes (FLSs) play a fundamental role in RA progression, through their expansion caused in part by resistance to cell death induction. The aim of our study was to determine the effects of different anti-TNF-alpha agents on FLS apoptosis.
Differential effects of anti-TNF-alpha drugs on fibroblast-like synoviocyte apoptosis / Pattacini, Laura; Boiardi, Luigi; Casali, Bruno; Salvarani, Carlo. - In: RHEUMATOLOGY. - ISSN 1462-0332. - 49:(2010), pp. 480-489. [10.1093/rheumatology/kep358]
Differential effects of anti-TNF-alpha drugs on fibroblast-like synoviocyte apoptosis
SALVARANI, CARLO
2010
Abstract
Novel drugs targeting TNF-alpha are available for treatment of RA. Fibroblast-like synoviocytes (FLSs) play a fundamental role in RA progression, through their expansion caused in part by resistance to cell death induction. The aim of our study was to determine the effects of different anti-TNF-alpha agents on FLS apoptosis.
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