Glucocorticoids are the mainstay of treatment of idiopathic retroperitoneal fibrosis, but they often have substantial toxic effects. Several reports have suggested tamoxifen as an alternative to glucocorticoids. We compared the efficacy of prednisone with that of tamoxifen in maintainance of remission in patients with idiopathic retroperitoneal fibrosis.
Prednisone versus tamoxifen in patients with idiopathic retroperitoneal fibrosis: an open-label randomised controlled trial / Vaglio, Augusto; Palmisano, Alessandra; Alberici, Federico; Maggiore, Umberto; Ferretti, Stefania; Cobelli, Rocco; Ferrozzi, Francesco; Corradi, Domenico; Salvarani, Carlo; Buzio, Carlo. - In: THE LANCET. - ISSN 0140-6736. - 378:(2011), pp. 338-346. [10.1016/S0140-6736(11)60934-3]
Prednisone versus tamoxifen in patients with idiopathic retroperitoneal fibrosis: an open-label randomised controlled trial
SALVARANI, CARLO;
2011-01-01
Abstract
Glucocorticoids are the mainstay of treatment of idiopathic retroperitoneal fibrosis, but they often have substantial toxic effects. Several reports have suggested tamoxifen as an alternative to glucocorticoids. We compared the efficacy of prednisone with that of tamoxifen in maintainance of remission in patients with idiopathic retroperitoneal fibrosis.
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