Using a genome-wide association scan and DNA pooling, we previously identified 5 novel genetic susceptibility loci for Behçet's disease. We undertook this study to establish the genetic effect within the UBAC2 gene, in the course of which we replicated this genetic association and identified a functional variant within this locus.
A putative functional variant within the UBAC2 gene is associated with increased risk of Behçet's disease / Sawalha, Amr H; Hughes, Travis; Nadig, Ajay; Yılmaz, Vuslat; Aksu, Kenan; Keser, Gokhan; Cefle, Ayse; Yazıcı, Ayten; Ergen, Andaç; Alarcón Riquelme, Marta E; Salvarani, Carlo; Casali, Bruno; Direskeneli, Haner; Saruhan Direskeneli, Güher. - In: ARTHRITIS AND RHEUMATISM. - ISSN 1529-0131. - 63:11(2011), pp. 3607-3612. [10.1002/art.30604]
A putative functional variant within the UBAC2 gene is associated with increased risk of Behçet's disease
SALVARANI, CARLO;
2011
Abstract
Using a genome-wide association scan and DNA pooling, we previously identified 5 novel genetic susceptibility loci for Behçet's disease. We undertook this study to establish the genetic effect within the UBAC2 gene, in the course of which we replicated this genetic association and identified a functional variant within this locus.
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