The “fate” of polymeric and lipid nanoparticles for brain delivery and targeting: Strategies and mechanism of blood–brain barrier crossing and trafficking into the central nervous system

Tosi, Giovanni; Musumeci, Teresa; Ruozi, Barbara; Carbone, Claudia; Belletti, Daniela; Pignatello, Rosario; Vandelli, Maria Angela; Puglisi, Giovanni

doi:10.1016/j.jddst.2015.07.007

Drug delivery to the brain represents one of the most important challenges in the field of nanomedicine, as the study and planning of nanocarriers able to cross the blood brain barrier are topics at the cutting edge of technology and innovation. In this review, we analyze the interventions and progresses in the field, by analyzing the choice of the polymer, of the ligands and the main relevant in vivo and in vitro experiments. A critical overview of these aspects will help in better understanding the status of nanomedicine in the application to central nervous system pathologies along with the future directions

Data di pubblicazione:	2016
Titolo:	The “fate” of polymeric and lipid nanoparticles for brain delivery and targeting: Strategies and mechanism of blood–brain barrier crossing and trafficking into the central nervous system
Autore/i:	Tosi, Giovanni; Musumeci, Teresa; Ruozi, Barbara; Carbone, Claudia; Belletti, Daniela; Pignatello, Rosario; Vandelli, Maria Angela; Puglisi, Giovanni
Autore/i UNIMORE:	TOSI, Giovanni Musumeci, Teresa RUOZI, Barbara Carbone, Claudia BELLETTI, Daniela Pignatello, Rosario VANDELLI, Maria Angela Puglisi, Giovanni mostra contributor esterni nascondi contributor esterni
Digital Object Identifier (DOI):	10.1016/j.jddst.2015.07.007
Rivista:	JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY
Volume:	32(Part B)
Pagina iniziale:	66
Pagina finale:	76
Codice identificativo ISI:	WOS:000374366000002
Codice identificativo Scopus:	2-s2.0-84961618744
Citazione:	The “fate” of polymeric and lipid nanoparticles for brain delivery and targeting: Strategies and mechanism of blood–brain barrier crossing and trafficking into the central nervous system / Tosi, Giovanni; Musumeci, Teresa; Ruozi, Barbara; Carbone, Claudia; Belletti, Daniela; Pignatello, Rosario; Vandelli, Maria Angela; Puglisi, Giovanni. - In: JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY. - ISSN 1773-2247. - STAMPA. - 32(Part B)(2016), pp. 66-76.
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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11380/1077148

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