Empiric antibiotic monotherapy is considered the standard of treatment for febrile neutropenic patients with cancer, but this approach may be inadequate because of the increasing prevalence of infections caused by multidrug resistant (MDR) bacteria.
Results of a multicenter, controlled, randomized clinical trial evaluating the combination of piperacillin/tazobactam and tigecycline in high-risk hematologic patients with cancer with febrile neutropenia / Bucaneve, Giampaolo; Micozzi, Alessandra; Picardi, Marco; Ballanti, Stelvio; Cascavilla, Nicola; Salutari, Prassede; Specchia, Giorgina; Fanci, Rosa; Luppi, Mario; Cudillo, Laura; Cantaffa, Renato; Milone, Giuseppe; Bocchia, Monica; Martinelli, Giovanni; Offidani, Massimo; Chierichini, Anna; Fabbiano, Francesco; Quarta, Giovanni; Primon, Valeria; Martino, Bruno; Manna, Annunziata; Zuffa, Eliana; Ferrari, Antonella; Gentile, Giuseppe; Foà, Robin; Del Favero, Albano. - In: JOURNAL OF CLINICAL ONCOLOGY. - ISSN 0732-183X. - STAMPA. - 32:(2014), pp. 1463-1471. [10.1200/JCO.2013.51.6963]
Results of a multicenter, controlled, randomized clinical trial evaluating the combination of piperacillin/tazobactam and tigecycline in high-risk hematologic patients with cancer with febrile neutropenia
LUPPI, Mario;
2014
Abstract
Empiric antibiotic monotherapy is considered the standard of treatment for febrile neutropenic patients with cancer, but this approach may be inadequate because of the increasing prevalence of infections caused by multidrug resistant (MDR) bacteria.
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