Cytarabine plays a pivotal role in the treatment of patients with acute myeloid leukemia (AML). Most centers use 7 to 10 days of cytarabine at a daily dose of 100 to 200 mg/m(2) for remission induction. Consensus has not been reached on the benefit of higher dosages of cytarabine.

High-dose cytarabine in induction treatment improves the outcome of adult patients younger than age 46 years with acute myeloid leukemia: results of the EORTC-GIMEMA AML-12 trial / Willemze, R., Suciu, S., Meloni, G., Labar, B., Marie, J.P., Halkes, C.J.M., Muus, P., Mistrik, M., Amadori, S., Specchia, G., Fabbiano, F., Nobile, F., Sborgia, M., Camera, A., Selleslag, D.L.D., Lefrère, F., Magro, D., Sica, S., Cantore, N., Beksac, M., et al.. - In: JOURNAL OF CLINICAL ONCOLOGY. - ISSN 0732-183X. - STAMPA. - 32:3(2014), pp. 219-228. [10.1200/JCO.2013.51.8571]

High-dose cytarabine in induction treatment improves the outcome of adult patients younger than age 46 years with acute myeloid leukemia: results of the EORTC-GIMEMA AML-12 trial

LUPPI, Mario;
2014

Abstract

Cytarabine plays a pivotal role in the treatment of patients with acute myeloid leukemia (AML). Most centers use 7 to 10 days of cytarabine at a daily dose of 100 to 200 mg/m(2) for remission induction. Consensus has not been reached on the benefit of higher dosages of cytarabine.
2014
Inglese
32
3
219
228
Adolescent; Adult; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Consolidation Chemotherapy; Cytarabine; Daunorubicin; Drug Administration Schedule; Etoposide; Europe; Female; Humans; Induction Chemotherapy; Infusions, Intravenous; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Risk Assessment; Risk Factors; Treatment Outcome
none
info:eu-repo/semantics/article
Contributo su RIVISTA::Articolo su rivista
262
High-dose cytarabine in induction treatment improves the outcome of adult patients younger than age 46 years with acute myeloid leukemia: results of the EORTC-GIMEMA AML-12 trial / Willemze, R., Suciu, S., Meloni, G., Labar, B., Marie, J.P., Halkes, C.J.M., Muus, P., Mistrik, M., Amadori, S., Specchia, G., Fabbiano, F., Nobile, F., Sborgia, M., Camera, A., Selleslag, D.L.D., Lefrère, F., Magro, D., Sica, S., Cantore, N., Beksac, M., et al.. - In: JOURNAL OF CLINICAL ONCOLOGY. - ISSN 0732-183X. - STAMPA. - 32:3(2014), pp. 219-228. [10.1200/JCO.2013.51.8571]
Willemze, Roelof; Suciu, Stefan; Meloni, Giovanna; Labar, Boris; Marie, Jean Pierre; Halkes, Constantijn J. M; Muus, Petra; Mistrik, Martin; Amadori, ...espandi
41
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1070267
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