TGF-β1 was inversely correlated with E-cadherin but significantly correlated with VEGF. VEGF and AFP had a low coefficient value but statistically significant. A significant correlation was found between E-cadherin and MMP2. In conclusion, TGF-β and E-cadherin are inversely correlated in HCC patients' sera and not related to the BCLC classification nor survival but rather to the biological properties of the tumor.

Circulating TGF-β1-related biomarkers in patients with hepatocellular carcinoma and their association with HCC staging scores / Dituri, Francesco; Serio, Gabriella; Filannino, Doriana; Mascolo, Antonella; Sacco, Rodolfo; Villa, Erica; Giannelli, Gianluigi. - In: CANCER LETTERS. - ISSN 0304-3835. - 353:(2014), pp. 264-271. [10.1016/j.canlet.2014.07.029]

Circulating TGF-β1-related biomarkers in patients with hepatocellular carcinoma and their association with HCC staging scores

VILLA, Erica;
2014

Abstract

TGF-β1 was inversely correlated with E-cadherin but significantly correlated with VEGF. VEGF and AFP had a low coefficient value but statistically significant. A significant correlation was found between E-cadherin and MMP2. In conclusion, TGF-β and E-cadherin are inversely correlated in HCC patients' sera and not related to the BCLC classification nor survival but rather to the biological properties of the tumor.
2014
353
264
271
Circulating TGF-β1-related biomarkers in patients with hepatocellular carcinoma and their association with HCC staging scores / Dituri, Francesco; Serio, Gabriella; Filannino, Doriana; Mascolo, Antonella; Sacco, Rodolfo; Villa, Erica; Giannelli, Gianluigi. - In: CANCER LETTERS. - ISSN 0304-3835. - 353:(2014), pp. 264-271. [10.1016/j.canlet.2014.07.029]
Dituri, Francesco; Serio, Gabriella; Filannino, Doriana; Mascolo, Antonella; Sacco, Rodolfo; Villa, Erica; Giannelli, Gianluigi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1066169
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