The role of carcinoembryonic antigen (CEA), magnetic resonance imaging (MRI), and positron emission tomography (PET)-computed tomography (CT) in detection of local recurrence of colorectal cancer is evaluated in 71 patients, selected due to suspected relapse at CT follow-up. Recurrence was confirmed by histology in 18 cases and excluded in 25 cases. Sensitivity, specificity, positive and negative predictive values, and accuracy were as follows: 44.4%, 92.5%, 66.7%, 83.1%, and 80.3% for CEA; 88.9%, 73.6%, 53.3%, 95.1%, and 77.5% for MRI; and 94.4%, 73.6%, 54.8%, 97.5%, and 78.9% for PET-CT. A diagnostic protocol integrating CEA and dedicated imaging studies is to be advocated.

Role of carcinoembryonic antigen, magnetic resonance imaging, and positron emission tomography-computed tomography in the evaluation of patients with suspected local recurrence of colorectal cancer / Fiocchi, Federica; Iotti, Valentina; Ligabue, Guido; Malavasi, Norma; Luppi, Gabriele; Bagni, Bruno; Torricelli, Pietro. - In: CLINICAL IMAGING. - ISSN 0899-7071. - STAMPA. - 35:4(2011), pp. 266-273. [10.1016/j.clinimag.2010.07.010]

Role of carcinoembryonic antigen, magnetic resonance imaging, and positron emission tomography-computed tomography in the evaluation of patients with suspected local recurrence of colorectal cancer

LIGABUE, Guido;MALAVASI, Norma;BAGNI, Bruno;TORRICELLI, Pietro
2011

Abstract

The role of carcinoembryonic antigen (CEA), magnetic resonance imaging (MRI), and positron emission tomography (PET)-computed tomography (CT) in detection of local recurrence of colorectal cancer is evaluated in 71 patients, selected due to suspected relapse at CT follow-up. Recurrence was confirmed by histology in 18 cases and excluded in 25 cases. Sensitivity, specificity, positive and negative predictive values, and accuracy were as follows: 44.4%, 92.5%, 66.7%, 83.1%, and 80.3% for CEA; 88.9%, 73.6%, 53.3%, 95.1%, and 77.5% for MRI; and 94.4%, 73.6%, 54.8%, 97.5%, and 78.9% for PET-CT. A diagnostic protocol integrating CEA and dedicated imaging studies is to be advocated.
2011
35
4
266
273
Role of carcinoembryonic antigen, magnetic resonance imaging, and positron emission tomography-computed tomography in the evaluation of patients with suspected local recurrence of colorectal cancer / Fiocchi, Federica; Iotti, Valentina; Ligabue, Guido; Malavasi, Norma; Luppi, Gabriele; Bagni, Bruno; Torricelli, Pietro. - In: CLINICAL IMAGING. - ISSN 0899-7071. - STAMPA. - 35:4(2011), pp. 266-273. [10.1016/j.clinimag.2010.07.010]
Fiocchi, Federica; Iotti, Valentina; Ligabue, Guido; Malavasi, Norma; Luppi, Gabriele; Bagni, Bruno; Torricelli, Pietro
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1064576
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