The use of stem cell progeny for transplantation for retinal regenerative therapy will require techniques to direct the differentiation of these cells toward specific retinal cell types. Adult retinal stem cells (RSCs) represent a promising source of cells for retinal cell therapy to treat blinding eye diseases. Here, we describe the use of combinations of exogenous culture additives to direct RSCs along photoreceptor and retinal pigment epithelial (RPE) lineages with high efficiency.
Directed differentiation of Photoreceptors and Retinal Pigment Epithelium from adult Mouse Retinal Stem Cells / Ballios, Brian G.; Marigo, Valeria; van der Kooy, Derek. - STAMPA. - (2015), pp. 129-135. [10.1002/9781118308295.ch14]
Directed differentiation of Photoreceptors and Retinal Pigment Epithelium from adult Mouse Retinal Stem Cells
MARIGO, Valeria;
2015
Abstract
The use of stem cell progeny for transplantation for retinal regenerative therapy will require techniques to direct the differentiation of these cells toward specific retinal cell types. Adult retinal stem cells (RSCs) represent a promising source of cells for retinal cell therapy to treat blinding eye diseases. Here, we describe the use of combinations of exogenous culture additives to direct RSCs along photoreceptor and retinal pigment epithelial (RPE) lineages with high efficiency.Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris