Colorectal cancers (CRCs) are frequently colonised by colibactin toxin-producing Escherichia coli bacteria that induce DNA damage in host cells and exhibit protumoural activities. Our objective was to identify small molecules inhibiting the toxic effects induced by these colibactin-producing bacteria.
Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria / Cougnoux, Antony; Delmas, Julien; Gibold, Lucie; Faïs, Tiphanie; Romagnoli, Chiara; Robin, Frederic; Cuevas Ramos, Gabriel; Oswald, Eric; Darfeuille Michaud, Arlette; Prati, Fabio; Dalmasso, Guillaume; Bonnet, Richard. - In: GUT. - ISSN 0017-5749. - ELETTRONICO. - 65:2(2016), pp. 278-285. [10.1136/gutjnl-2014-307241]
Small-molecule inhibitors prevent the genotoxic and protumoural effects induced by colibactin-producing bacteria
PRATI, Fabio;
2016
Abstract
Colorectal cancers (CRCs) are frequently colonised by colibactin toxin-producing Escherichia coli bacteria that induce DNA damage in host cells and exhibit protumoural activities. Our objective was to identify small molecules inhibiting the toxic effects induced by these colibactin-producing bacteria.File | Dimensione | Formato | |
---|---|---|---|
VOR_Small-molecule inhibitors prevent the genotoxic.pdf
Accesso riservato
Tipologia:
Versione pubblicata dall'editore
Dimensione
2.97 MB
Formato
Adobe PDF
|
2.97 MB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris