In previous studies, the present group showed that a factor, present in the cerebrospinal fluid of seven neuro-patients, was capable of inducing cell damages on cell cultures of epithelial cells (Vero), glial cells (DG54-MG) and human primary lymphocytes. The cytotoxicity, once induced, could be transmitted to fresh cell cultures using crude preparations obtained from the cytotoxic cell cultures.

Electron microscope study on a transmissible cytotoxic factor isolated from cerebrospinal fluid of neurological patients: analysis of its structure and of its effects on various types of cell cultures / Guerra, Deanna; Ronchetti, Ivonne; Beretti, Francesca; Bartoletti, Anna Maria; Pietrosemoli, Paola; Gelormini, M. S; Malagolini, N; Muscatello, Umberto; Portolani, Marinella. - In: JOURNAL OF CLINICAL PATHOLOGY. - ISSN 0021-9746. - STAMPA. - 65:(2012), pp. 20-28. [10.1136/jclinpath-2011-200034]

Electron microscope study on a transmissible cytotoxic factor isolated from cerebrospinal fluid of neurological patients: analysis of its structure and of its effects on various types of cell cultures

GUERRA, Deanna;RONCHETTI, Ivonne;BERETTI, Francesca;MUSCATELLO, Umberto;PORTOLANI, Marinella
2012-01-01

Abstract

In previous studies, the present group showed that a factor, present in the cerebrospinal fluid of seven neuro-patients, was capable of inducing cell damages on cell cultures of epithelial cells (Vero), glial cells (DG54-MG) and human primary lymphocytes. The cytotoxicity, once induced, could be transmitted to fresh cell cultures using crude preparations obtained from the cytotoxic cell cultures.
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Electron microscope study on a transmissible cytotoxic factor isolated from cerebrospinal fluid of neurological patients: analysis of its structure and of its effects on various types of cell cultures / Guerra, Deanna; Ronchetti, Ivonne; Beretti, Francesca; Bartoletti, Anna Maria; Pietrosemoli, Paola; Gelormini, M. S; Malagolini, N; Muscatello, Umberto; Portolani, Marinella. - In: JOURNAL OF CLINICAL PATHOLOGY. - ISSN 0021-9746. - STAMPA. - 65:(2012), pp. 20-28. [10.1136/jclinpath-2011-200034]
Guerra, Deanna; Ronchetti, Ivonne; Beretti, Francesca; Bartoletti, Anna Maria; Pietrosemoli, Paola; Gelormini, M. S; Malagolini, N; Muscatello, Umberto; Portolani, Marinella
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1063589
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