Follicle stimulating hormone (FSH) is a glycoprotein hormone essential for reproduction both in females and males and it is physiologically produced by the anterior pituitary gland in several isoforms. This heterogeneity is typical also of FSH-containing compounds, both urinary-derived and recombinant products. These compounds are widely used in assisted reproductive technologies (ART), to induce multifollicular development. Recently, the increased cost pressure on healthcare systems and the patent expiration date of widely used biotechnology-derived, recombinant FSH, prompted the pharmaceutical interest in FSH biosimilars.

Biosimilar recombinant follicle stimulating hormones in infertility treatment / Santi, Daniele; Simoni, Manuela. - In: EXPERT OPINION ON BIOLOGICAL THERAPY. - ISSN 1471-2598. - STAMPA. - 14:10(2014), pp. 1399-1409. [10.1517/14712598.2014.925872]

Biosimilar recombinant follicle stimulating hormones in infertility treatment

SANTI, Daniele;SIMONI, Manuela
2014

Abstract

Follicle stimulating hormone (FSH) is a glycoprotein hormone essential for reproduction both in females and males and it is physiologically produced by the anterior pituitary gland in several isoforms. This heterogeneity is typical also of FSH-containing compounds, both urinary-derived and recombinant products. These compounds are widely used in assisted reproductive technologies (ART), to induce multifollicular development. Recently, the increased cost pressure on healthcare systems and the patent expiration date of widely used biotechnology-derived, recombinant FSH, prompted the pharmaceutical interest in FSH biosimilars.
2014
14
10
1399
1409
Biosimilar recombinant follicle stimulating hormones in infertility treatment / Santi, Daniele; Simoni, Manuela. - In: EXPERT OPINION ON BIOLOGICAL THERAPY. - ISSN 1471-2598. - STAMPA. - 14:10(2014), pp. 1399-1409. [10.1517/14712598.2014.925872]
Santi, Daniele; Simoni, Manuela
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1063414
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