Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract

Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K; Nylander, Olof; Vergoni, Anna Valeria; Schiöth, Helgi B.

doi:10.1186/1471-230X-12-134

G protein-coupled receptors (GPCRs) represent one of the largest families of transmembrane receptors and the most common drug target. The Adhesion subfamily is the second largest one of GPCRs and its several members are known to mediate neural development and immune system functioning through cell-cell and cell-matrix interactions. The distribution of these receptors has not been characterized in detail in the gastrointestinal (GI) tract. Here we present the first comprehensive anatomical profiling of mRNA expression of all 30 Adhesion GPCRs in the rat GI tract divided into twelve subsegments.

Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract / Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K; Nylander, Olof; Vergoni, Anna Valeria; Schiöth, Helgi B.. - In: BMC GASTROENTEROLOGY. - ISSN 1471-230X. - STAMPA. - 12(2012), pp. 134-144.

Data di pubblicazione:	2012
Titolo:	Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract
Autore/i:	Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K; Nylander, Olof; Vergoni, Anna Valeria; Schiöth, Helgi B.
Autore/i UNIMORE:	Badiali, Luca Cedernaes, Jonathan Olszewski, Pawel K Nylander, Olof VERGONI, Anna Valeria Schiöth, Helgi B. mostra contributor esterni nascondi contributor esterni
Digital Object Identifier (DOI):	http://dx.doi.org/10.1186/1471-230X-12-134
Rivista:	BMC GASTROENTEROLOGY
Volume:	12
Pagina iniziale:	134
Pagina finale:	144
Codice identificativo ISI:	WOS:000312734600001
Codice identificativo Scopus:	2-s2.0-84866547948
Codice identificativo Pubmed:	23009096
Citazione:	Adhesion GPCRs are widely expressed throughout the subsections of the gastrointestinal tract / Badiali, Luca; Cedernaes, Jonathan; Olszewski, Pawel K; Nylander, Olof; Vergoni, Anna Valeria; Schiöth, Helgi B.. - In: BMC GASTROENTEROLOGY. - ISSN 1471-230X. - STAMPA. - 12(2012), pp. 134-144.
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Utilizza questo identificativo per citare o creare un link a questo documento:
http://hdl.handle.net/11380/1063135

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