Because chronic obstructive pulmonary disease (COPD) is defined as an inflammatory disease,1 anti-inflammatory therapy for these patients makes sense. Inhaled corticosteroids are well established anti-inflammatory drugs in asthma2 but their positioning in COPD is controversial.3 There is consensus that inhaled corticosteroids in combination with long-acting bronchodilators are indicated in patients with COPD at risk of exacerbation and in those with the asthma–COPD overlap syndrome, but never as standalone therapy.
Inhaled steroids in COPD: when should they be used? / Agusti, Alvar; Fabbri, Leonardo. - In: THE LANCET RESPIRATORY MEDICINE. - ISSN 2213-2600. - STAMPA. - 2:11(2014), pp. 869-871. [10.1016/S2213-2600(14)70227-9]
Inhaled steroids in COPD: when should they be used?
FABBRI, Leonardo
2014
Abstract
Because chronic obstructive pulmonary disease (COPD) is defined as an inflammatory disease,1 anti-inflammatory therapy for these patients makes sense. Inhaled corticosteroids are well established anti-inflammatory drugs in asthma2 but their positioning in COPD is controversial.3 There is consensus that inhaled corticosteroids in combination with long-acting bronchodilators are indicated in patients with COPD at risk of exacerbation and in those with the asthma–COPD overlap syndrome, but never as standalone therapy.
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