Here, we investigate the in vitro biocompatibility of polyvinylidenefluoride (PVDF)–polytrifluoroethylene (PTrFE) copolymer thin films using neuronal cells. The aim is to obtain an optimal capping layer material for hybrid bio-organic electronic transducers based on organic electronic devices, which can be applied for bidirectional communication with the central nervous system. PVDF:PTrFE thin films were grown by spin coating and characterized by AFM. Human neuroblastoma SHSY5Y cells were used as neuronal model and their interaction with PVDF:PTrFE films was investigated in term of cell adhesion, proliferation, differentiation, and cytoskeleton organization. We show that PVDF:PTrFE thin films allowed standard SHSY5Y proliferation and neuronal differentiation, even if with reduced short-term cell adhesion and spreading.
Human Neuronal SHSY5Y Cells on PVDF:PTrFE Copolymer Thin Films / Tonazzini, Ilaria; Bystrenova, Eva; Chelli, Beatrice; Greco, Pierpaolo; De Leeuw, Dago; Biscarini, Fabio. - In: ADVANCED ENGINEERING MATERIALS. - ISSN 1527-2648. - STAMPA. - n/a(2015), pp. N/A-n/a. [10.1002/adem.201400441]
Data di pubblicazione: | 2015 | |
Titolo: | Human Neuronal SHSY5Y Cells on PVDF:PTrFE Copolymer Thin Films | |
Autore/i: | Tonazzini, Ilaria; Bystrenova, Eva; Chelli, Beatrice; Greco, Pierpaolo; De Leeuw, Dago; Biscarini, Fabio | |
Autore/i UNIMORE: | ||
Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/adem.201400441 | |
Rivista: | ||
Volume: | n/a | |
Pagina iniziale: | N/A | |
Pagina finale: | n/a | |
Codice identificativo ISI: | WOS:000357680700016 | |
Codice identificativo Scopus: | 2-s2.0-84935504314 | |
Citazione: | Human Neuronal SHSY5Y Cells on PVDF:PTrFE Copolymer Thin Films / Tonazzini, Ilaria; Bystrenova, Eva; Chelli, Beatrice; Greco, Pierpaolo; De Leeuw, Dago; Biscarini, Fabio. - In: ADVANCED ENGINEERING MATERIALS. - ISSN 1527-2648. - STAMPA. - n/a(2015), pp. N/A-n/a. [10.1002/adem.201400441] | |
Tipologia | Articolo su rivista |
File in questo prodotto:
Pubblicazioni consigliate

I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris