Different therapeutic strategies are available for treatment of multiple sclerosis (MS) including immunosuppressants, immunomodulators, and monoclonal antibodies. Their relative effectiveness in the prevention of relapse or disability progression is unclear due to the limited number of direct comparison trials. A summary of the results, including both direct and indirect comparisons of treatment effects, may help to clarify the above uncertainty.
Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis / Filippini, Graziella; DEL GIOVANE, Cinzia; Vacchi, Laura; D'Amico, Roberto; Di Pietrantonj, Carlo; Beecher, Deirdre; Salanti, Georgia. - In: COCHRANE DATABASE OF SYSTEMATIC REVIEWS. - ISSN 1469-493X. - STAMPA. - 2013:6(2013), pp. CD008933-CD008933. [10.1002/14651858.CD008933.pub2]
Immunomodulators and immunosuppressants for multiple sclerosis: a network meta-analysis
DEL GIOVANE, Cinzia;D'AMICO, Roberto;
2013
Abstract
Different therapeutic strategies are available for treatment of multiple sclerosis (MS) including immunosuppressants, immunomodulators, and monoclonal antibodies. Their relative effectiveness in the prevention of relapse or disability progression is unclear due to the limited number of direct comparison trials. A summary of the results, including both direct and indirect comparisons of treatment effects, may help to clarify the above uncertainty.
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