dermoscopic criteria associated with BRAF and NRAS mutation status in primary cutaneous melanoma have been recently analyzed by Pozzobon et al. in an interesting study published in your journal. The authors found out that peppering pattern was significantly increased among BRAF mutant melanoma, being present in the 68% of their cases series, with OR 1.68 (CI 95%1.089-2.581, p=0.015).1 The intend of this letter is to underline the dermoscopic features and the distinctive clinical features of BRAF p.V600K melanoma (the second most common BRAF V600 mutation detected in 5 to 30% of cases), that might be slightly different from from BRAF p.V600E melanoma.
Distinctive clinical and dermoscopic features of BRAFp.V600K mutated melanomas / Ponti, Giovanni; Manfredini, M; Tomasi, Aldo; Pellacani, Giovanni. - In: BRITISH JOURNAL OF DERMATOLOGY. - ISSN 0007-0963. - STAMPA. - 172:5(2015), pp. 1438-1440. [10.1111/bjd.13484]
Distinctive clinical and dermoscopic features of BRAFp.V600K mutated melanomas.
PONTI, Giovanni;Manfredini M;TOMASI, Aldo;PELLACANI, Giovanni
2015
Abstract
dermoscopic criteria associated with BRAF and NRAS mutation status in primary cutaneous melanoma have been recently analyzed by Pozzobon et al. in an interesting study published in your journal. The authors found out that peppering pattern was significantly increased among BRAF mutant melanoma, being present in the 68% of their cases series, with OR 1.68 (CI 95%1.089-2.581, p=0.015).1 The intend of this letter is to underline the dermoscopic features and the distinctive clinical features of BRAF p.V600K melanoma (the second most common BRAF V600 mutation detected in 5 to 30% of cases), that might be slightly different from from BRAF p.V600E melanoma.File | Dimensione | Formato | |
---|---|---|---|
bjd.13484.pdf
Accesso riservato
Tipologia:
Versione pubblicata dall'editore
Dimensione
523.42 kB
Formato
Adobe PDF
|
523.42 kB | Adobe PDF | Visualizza/Apri Richiedi una copia |
Pubblicazioni consigliate
I metadati presenti in IRIS UNIMORE sono rilasciati con licenza Creative Commons CC0 1.0 Universal, mentre i file delle pubblicazioni sono rilasciati con licenza Attribuzione 4.0 Internazionale (CC BY 4.0), salvo diversa indicazione.
In caso di violazione di copyright, contattare Supporto Iris