Background In the human diet, consumption of fresh fruits and vegetables is important in maintaining a good health status and in preventing chronic diseases. It is known that plant derived food is a powerful source of chemopreventive molecules i.e. antioxidants, and spinach (Spinacia oleracea L., Chenopodiaceae) possesses a wide range of metabolites with such biological activity. Plant stress response could lead to the production of metabolites with high value for human health and this could be a tool to enhance the production of molecules with antioxidant activity in plants. Results Data reported in this paper confirm the antioxidant properties of spinach plants, and show a strong antiproliferative activity of leaf extract on HT-29 human cell line. Besides, the hypoxic stress seems to affect the pool of antioxidant molecules present in spinach leaves, as verified by means of HPLC-MS/MS analysis and the aluminium chloride and ABTS assays. Conclusion Our findings - represents a hint for an improvement in the biological and pharmacological properties of spinach plants, being the growth condition a strategy to modulate the spinach phytocomplex profile.

Assessment of antioxidant and antiproliferative properties of spinach plants grown under low oxygen availability / Fornaciari, Silvia; Milano, F.; Mussi, Francesca; Pinto Sanchez, L.; Forti, Luca; Buschini, A.; Arru, Laura. - In: JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE. - ISSN 1097-0010. - ELETTRONICO. - 95:3(2015), pp. 490-496. [10.1002/jsfa.6756]

Assessment of antioxidant and antiproliferative properties of spinach plants grown under low oxygen availability

FORNACIARI, Silvia;MUSSI, FRANCESCA;FORTI, Luca;ARRU, Laura
2015

Abstract

Background In the human diet, consumption of fresh fruits and vegetables is important in maintaining a good health status and in preventing chronic diseases. It is known that plant derived food is a powerful source of chemopreventive molecules i.e. antioxidants, and spinach (Spinacia oleracea L., Chenopodiaceae) possesses a wide range of metabolites with such biological activity. Plant stress response could lead to the production of metabolites with high value for human health and this could be a tool to enhance the production of molecules with antioxidant activity in plants. Results Data reported in this paper confirm the antioxidant properties of spinach plants, and show a strong antiproliferative activity of leaf extract on HT-29 human cell line. Besides, the hypoxic stress seems to affect the pool of antioxidant molecules present in spinach leaves, as verified by means of HPLC-MS/MS analysis and the aluminium chloride and ABTS assays. Conclusion Our findings - represents a hint for an improvement in the biological and pharmacological properties of spinach plants, being the growth condition a strategy to modulate the spinach phytocomplex profile.
2015
24-mag-2014
95
3
490
496
Assessment of antioxidant and antiproliferative properties of spinach plants grown under low oxygen availability / Fornaciari, Silvia; Milano, F.; Mussi, Francesca; Pinto Sanchez, L.; Forti, Luca; Buschini, A.; Arru, Laura. - In: JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE. - ISSN 1097-0010. - ELETTRONICO. - 95:3(2015), pp. 490-496. [10.1002/jsfa.6756]
Fornaciari, Silvia; Milano, F.; Mussi, Francesca; Pinto Sanchez, L.; Forti, Luca; Buschini, A.; Arru, Laura
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11380/1018714
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