Background and aims: To assess out the clinical impact of 25(OH)D plasma levels < 20ng/mL in HIV-infected pregnant women and their newborns. Methods: Cross-sectional study. Quantitative determinations of 25(OH)D were measured using chemiluminescent immunoassay technology in HIV-infected pregnant women at third trimester, participating between 2003 and 2010 to the Italian National Program on Surveillance on Antiretroviral Treatment in Pregnancy. Results: One hundred seventeen HIV-infected pregnant women were studied. 25(OH)D mean value(±SD) was 19.89(±11.36)ng/mL. Prevalence of 25(OH)D levels < 20ng/mL was 64.1%. Preterm delivery (< 37weeks) occurred in 15.38% of the women. There was no statistically significant association between low 25(OH)D and pregnancy outcomes at multivariate analysis (Table1). Conclusion: This study shows a high prevalence of 25(OH)D deficiency. Future studies are needed to verify potential role of low 25(OH)D in determining birth weight in HIV-infected pregnant women.
HIGH PREVALENCE OF VITAMIN D DEFICIENCY IN A COHORT OF HIV INFECTED PREGNANT WOMEN AND ITS IMPACT ON PREGNANCY OUTCOME / Stentarelli, Chiara; Zona, Stefano; E., Garlassi; Menozzi, Marianna; T., Trenti; S., Baroncelli; C., Pinnetti; A., Degli Antoni; M., Floridia; Guaraldi, Giovanni. - (2013), pp. na-na.
HIGH PREVALENCE OF VITAMIN D DEFICIENCY IN A COHORT OF HIV INFECTED PREGNANT WOMEN AND ITS IMPACT ON PREGNANCY OUTCOME
STENTARELLI, Chiara;ZONA, Stefano;Menozzi, Marianna;GUARALDI, Giovanni
2013
Abstract
Background and aims: To assess out the clinical impact of 25(OH)D plasma levels < 20ng/mL in HIV-infected pregnant women and their newborns. Methods: Cross-sectional study. Quantitative determinations of 25(OH)D were measured using chemiluminescent immunoassay technology in HIV-infected pregnant women at third trimester, participating between 2003 and 2010 to the Italian National Program on Surveillance on Antiretroviral Treatment in Pregnancy. Results: One hundred seventeen HIV-infected pregnant women were studied. 25(OH)D mean value(±SD) was 19.89(±11.36)ng/mL. Prevalence of 25(OH)D levels < 20ng/mL was 64.1%. Preterm delivery (< 37weeks) occurred in 15.38% of the women. There was no statistically significant association between low 25(OH)D and pregnancy outcomes at multivariate analysis (Table1). Conclusion: This study shows a high prevalence of 25(OH)D deficiency. Future studies are needed to verify potential role of low 25(OH)D in determining birth weight in HIV-infected pregnant women.Pubblicazioni consigliate
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