ROMAGNOLI, Chiara

ROMAGNOLI, Chiara  

Dipartimento di Scienze della Vita  

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A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amts. of at least one β-lactam antibiotic and at least one triazolylmethyl boronic acid β-lactamase inhibitor. 6-set-2016 Bonomo, Robert; Prati, Fabio; Caselli, Emilia; Romagnoli, Chiara
Biochemical and structural analysis of inhibitors targeting the ADC-7 cephalosporinase of Acinetobacter baumannii 1-gen-2014 R. A., Powers; H. C., Swanson; M. A., Taracila; N. W., Florek; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; R. A., Bonomo; B. J., Wallar
Boronic acid transition state inhibitors active against KPC and other class a β-lactamases: Structure-activity relationships as a guide to inhibitor design 1-gen-2016 Rojas, Laura J.; Taracila, Magdalena A.; Papp Wallace, Krisztina M.; Bethel, Christopher R.; Caselli, Emilia; Romagnoli, Chiara; Winkler, Marisa L.; Spellberg, Brad; Prati, Fabio; Bonomo, Robert A.
Click Chemistry in Lead Optimization of Boronic Acids as β-Lactamase Inhibitors 1-gen-2015 Caselli, Emilia; Romagnoli, Chiara; Vahabi, Roza; Taracila, Magdalena A; Bonomo, Robert A; Prati, Fabio
Crystal structures of KPC-2 and SHV-1 β-lactamases in complex with the boronic acid transition state analog S02030 1-gen-2016 Nguyen, Nhu Q.; Krishnan, Nikhil P.; Rojas, Laura J.; Prati, Fabio; Caselli, Emilia; Romagnoli, Chiara; Bonomo, Robert A.; Van Den Akker, Focco
Design and exploration of novel boronic acid Inhibitors reveals important Interactions with a clavulanic acid-resistant sulfhydryl- variable (SHV) β‑ lactamase 1-gen-2013 Marisa L., Winkler; Elizabeth A., Rodkey; Magdalena A., Taracila; Sarah M., Drawz; Christopher R., Bethel; Krisztina M., Papp Wallace; Kerri M., Smith; Yan, Xu; Jeffrey R., Dwulit Smith; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; Focco van den, Akker; Robert A., Bonomo
Design, synthesis, crystal structures and antimicrobial activity of sulfonamide boronic acids as beta-lactamase inhibitors 1-gen-2010 Oliv, Eidam; Romagnoli, Chiara; Caselli, Emilia; Joel, Karpiak; Kerim, Babaoglu; Denise Teotico, Pohlhaus; Richard, Bonnet; Brian K., Shoichet; Prati, Fabio
Fragment-guided Design of Subnanomolar β-Lactamase Inhibitors Active in vivo 1-gen-2012 O., Eidam; Romagnoli, Chiara; G., Dalmasso; S., Barelier; Caselli, Emilia; R., Bonnet; B. K., Shoichet; Prati, Fabio
Inhibiting the β-Lactamase of Mycobacterium tuberculosis (Mtb) with Novel Boronic Acid Transition-State Inhibitors (BATSIs) 1-gen-2015 Kurz, Sebastian G.; Hazra, Saugata; Bethel, Christopher R.; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; Blanchard, John S.; Bonomo, Robert A.
Inhibition of Acinetobacter -Derived Cephalosporinase: Exploring the Carboxylate Recognition Site Using Novel β-Lactamase Inhibitors 1-gen-2018 Caselli, Emilia; Romagnoli, Chiara; Powers, Rachel A.; Taracila, Magdalena A.; Bouza, Alexandra A.; Swanson, Hollister C.; Smolen, Kali A.; Fini, Francesco; Wallar, Bradley J.; Bonomo, Robert A.; Prati, Fabio
Paternó-Büchi reaction versus hydrogen abstraction in the photochemical reactivity of alkenyl boronates with benzophenone 1-gen-2013 A., D’Annibale; M., D’Auria; Prati, Fabio; Romagnoli, Chiara; S., Stoia; R., Racioppi; L., Viggiani
Structure-Based Analysis of Boronic Acids as Inhibitors of Acinetobacter-Derived Cephalosporinase-7, a Unique Class C β-Lactamase 1-gen-2018 Bouza, Alexandra A; Swanson, Hollister C; Smolen, Kali A; Vandine, Alison L; Taracila, Magdalena A; Romagnoli, Chiara; Caselli, Emilia; Prati, Fabio; Bonomo, Robert A; Powers, Rachel A; Wallar, Bradley J
Sulfonamido-substituted boronic acids as β-lactamase inhibitors for treatment of antibiotic-resistant bacterial infections - Shoichet Brian, K; Prati, Fabio; Caselli, Emilia; Romagnoli, Chiara; Eidam, Oliv
Synthesis, characterization and metal coordination of a potential β-lactamase inhibitor: 5-Methyl-2-phenoxymethyl-3-H-imidazole-4-carboxylic acid (PIMA) 1-gen-2017 Romagnoli, Chiara; Prati, Fabio; Benassi, Rois; Orteca, Giulia; Saladini, Monica; Ferrari, Erika