| Nome |
# |
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Profiling of Flavonol Derivatives for the Development of Antitrypanosomatidic Drugs, file e31e124b-f9cb-987f-e053-3705fe0a095a
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535
|
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Hits and Lead Discovery in the Identification of New Drugs against the Trypanosomatidic Infections, file e31e124d-e223-987f-e053-3705fe0a095a
|
371
|
|
Current and Future Chemotherapy for Chagas Disease, file e31e124b-f788-987f-e053-3705fe0a095a
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336
|
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Protein–protein interface-binding peptides inhibit the cancer therapy target human thymidylate synthase, file e31e124b-6883-987f-e053-3705fe0a095a
|
277
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Modulation of the expression of folate cycle enzymes and polyamine metabolism by berberine in cisplatin-sensitive and -resistant human ovarian cancer cells, file e31e124b-3ceb-987f-e053-3705fe0a095a
|
213
|
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Exploiting the 2-Amino-1,3,4-thiadiazole Scaffold To InhibitTrypanosoma bruceiPteridine Reductase in Support of Early-Stage Drug Discovery, file e31e124d-29e1-987f-e053-3705fe0a095a
|
207
|
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Accelerating Drug Discovery Efforts for Trypanosomatidic Infections Using an Integrated Transnational Academic Drug Discovery Platform, file e31e124d-a882-987f-e053-3705fe0a095a
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179
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Discovery of potent pteridine reductase inhibitors to guide antiparasite drug development, file e31e124a-99d6-987f-e053-3705fe0a095a
|
169
|
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Proteomic and bioinformatic studies for the characterization of response to pemetrexed in platinum drug resistant ovarian cancer, file e31e124d-83f4-987f-e053-3705fe0a095a
|
150
|
|
Inhibitor Specificity via Protein Dynamics. Insights from the Design of Antibacterial Agents Targeted Against Thymidylate Synthase, file e31e124b-fba7-987f-e053-3705fe0a095a
|
140
|
|
Intrinsic Fluorescence of the Active and the Inactive Functional Forms of Human Thymidylate Synthase, file e31e124f-8954-987f-e053-3705fe0a095a
|
136
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“A step further in the discovery of phthalein derivatives as Thymidylate Synthase inhibitors”, file e31e124b-f1bd-987f-e053-3705fe0a095a
|
131
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|
X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors, file e31e124c-1304-987f-e053-3705fe0a095a
|
107
|
|
2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1, file e31e1250-3f58-987f-e053-3705fe0a095a
|
69
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SAR Studies and Biological Characterization of a Chromen-4-one Derivative as an Anti-Trypanosoma brucei Agent, file e31e124d-a229-987f-e053-3705fe0a095a
|
62
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Enhancement of Benzothiazoles as Pteridine Reductase-1 Inhibitors for the Treatment of Trypanosomatidic Infections, file e31e1250-0d79-987f-e053-3705fe0a095a
|
42
|
|
Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase, file e31e1250-aac5-987f-e053-3705fe0a095a
|
40
|
|
Peptides binding to the dimer interface of thymidylate synthase for the treatment of cancer-US8916679 “B2 - Granted patent as second publication”., file e31e124a-c526-987f-e053-3705fe0a095a
|
38
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Aryl thiosemicarbazones for the treatment of trypanosomatidic infections, file e31e1250-6145-987f-e053-3705fe0a095a
|
36
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Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds, file e31e1250-3ee5-987f-e053-3705fe0a095a
|
27
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Compounds having antiparasitic activity, file e31e124d-efcc-987f-e053-3705fe0a095a
|
19
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Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth, file a2cae1de-bd1b-426b-91e9-1b996303dd0b
|
15
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Destabilizers of the thymidylate synthase homodimer accelerate its proteasomal degradation and inhibit cancer growth, file aa21c5db-c206-459d-83d7-a5a0a3c06e02
|
13
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Hotspots in an obligate homodimeric anticancer target. structural and functional effects of interfacial mutations in human thymidylate synthase, file e31e124f-c717-987f-e053-3705fe0a095a
|
10
|
|
Comparing Drug Images and Repurposing Drugs with BioGPS and FLAPdock: The Thymidylate Synthase Case, file e31e124b-f786-987f-e053-3705fe0a095a
|
5
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2-Carboxyquinoxalines Kill Mycobacterium tuberculosis through Noncovalent Inhibition of DprE1, file e31e124b-f9f3-987f-e053-3705fe0a095a
|
5
|
|
Ligand-based discovery of N-(1,3-dioxo-1H,3H-benzo[de]isochromen-5-yl)-carboxamide and sulfonamide derivatives as thymidylate synthase A inhibitors, file e31e124a-a843-987f-e053-3705fe0a095a
|
4
|
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Hotspots in an obligate homodimeric anticancer target. structural and functional effects of interfacial mutations in human thymidylate synthase, file e31e124b-f246-987f-e053-3705fe0a095a
|
4
|
|
Virtual Screening and X-ray Crystallography Identify Non-Substrate Analog Inhibitors of Flavin-Dependent Thymidylate Synthase, file e31e124b-f3e1-987f-e053-3705fe0a095a
|
4
|
|
Methoxylated 2'-hydroxychalcones as antiparasitic hit compounds, file e31e124d-29f9-987f-e053-3705fe0a095a
|
4
|
|
Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase, file e31e124b-6cb5-987f-e053-3705fe0a095a
|
3
|
|
2-[N-Alkyl(R-phenyl)-aminomethyl]-3-phenyl-7-trifluoromethylquinoxalines as anticancer agents inhibitors of folate enzymes, file e31e124b-f2bd-987f-e053-3705fe0a095a
|
3
|
|
X-ray crystal structures of Enterococcus faecalis thymidylate synthase with folate binding site inhibitors, file e31e124b-fc95-987f-e053-3705fe0a095a
|
3
|
|
ANTICANCER DRUGS, file e31e124d-a391-987f-e053-3705fe0a095a
|
3
|
|
Improving specificity vs bacterial thymidylate synthases through N-dansyl modulation of didansyltyrosine, file e31e124a-9542-987f-e053-3705fe0a095a
|
2
|
|
Update on antifolate drugs targets, file e31e124b-f14e-987f-e053-3705fe0a095a
|
2
|
|
Antibacterial agent discovery using thymidylate synthase biolibrary screening, file e31e124b-f1bf-987f-e053-3705fe0a095a
|
2
|
|
Biochemical effects of riluzole on Leishmania parasites, file e31e124b-f509-987f-e053-3705fe0a095a
|
2
|
|
The Hippo Pathway and YAP/TAZ-TEAD Protein-Protein Interaction as Targets for Regenerative Medicine and Cancer Treatment, file e31e124b-fd39-987f-e053-3705fe0a095a
|
2
|
|
Aryl thiosemicarbazones for the treatment of trypanosomatidic infections, file e31e124d-25ba-987f-e053-3705fe0a095a
|
2
|
|
Biochemistry: Anchors away, file e31e124a-a110-987f-e053-3705fe0a095a
|
1
|
|
Dimer-monomer equilibrium of human thymidylate synthase monitored by fluorescenceresonance energy transfer., file e31e124a-a297-987f-e053-3705fe0a095a
|
1
|
|
Optimization of Peptides That Target Human Thymidylate Synthase
to Inhibit Ovarian Cancer Cell Growth, file e31e124b-3ce9-987f-e053-3705fe0a095a
|
1
|
|
Internalization and stability of a thymidylate synthase peptide inhibitor in ovarian cancer cells, file e31e124b-a730-987f-e053-3705fe0a095a
|
1
|
|
Thymidylate synthase structure, function and implication in drug discovery, file e31e124b-f1af-987f-e053-3705fe0a095a
|
1
|
|
Constrained dansyl derivatives reveal bacterial specificity of highly conserved Thymidylate Synthases A, file e31e124b-f1c1-987f-e053-3705fe0a095a
|
1
|
|
Target-based approaches for the discovery of new antimycobacterial drugs, file e31e124d-234c-987f-e053-3705fe0a095a
|
1
|
|
Inside the biochemical pathways of thymidylate synthase perturbed by anticancer drugs: Novel strategies to overcome cancer chemoresistance, file e31e124f-488f-987f-e053-3705fe0a095a
|
1
|
|
Current and Future Chemotherapy for Chagas Disease, file e31e124f-91b5-987f-e053-3705fe0a095a
|
1
|
|
Current and Future Chemotherapy for Chagas Disease, file e31e124f-a820-987f-e053-3705fe0a095a
|
1
|
|
Current and Future Chemotherapy for Chagas Disease, file e31e124f-a821-987f-e053-3705fe0a095a
|
1
|
| Totale |
3.383 |
